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PTPRO protein tyrosine phosphatase receptor type O [ Zalophus californianus (California sea lion) ]

Gene ID: 113922700, updated on 15-Mar-2024

Summary

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Gene symbol
PTPRO
Gene description
protein tyrosine phosphatase receptor type O
See related
EnsemblRapid:ENSZCAG00025022427
Gene type
protein coding
RefSeq status
MODEL
Organism
Zalophus californianus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Otariidae; Zalophus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 9
Exon count:
28
Annotation release Status Assembly Chr Location
101 current mZalCal1.pri.v2 (GCF_009762305.2) 9 NC_045603.1 (90653127..90892301, complement)
100 previous assembly zalCal2.2 (GCF_900631625.1) Unplaced Scaffold NW_020884870.1 (48093461..48332798)

Chromosome 9 - NC_045603.1Genomic Context describing neighboring genes Neighboring gene serine/threonine kinase receptor associated protein Neighboring gene EGFR pathway substrate 8, signaling adaptor Neighboring gene RAS like estrogen regulated growth inhibitor Neighboring gene Rho GDP dissociation inhibitor beta Neighboring gene phosphodiesterase 6H

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in podocyte differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of glomerular filtration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in GABA-ergic synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
receptor-type tyrosine-protein phosphatase O

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Zalophus californianus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mZalCal1.pri.v2 Primary Assembly

Genomic

  1. NC_045603.1 Reference mZalCal1.pri.v2 Primary Assembly

    Range
    90653127..90892301 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_027594901.2 → XP_027450702.1  receptor-type tyrosine-protein phosphatase O isoform X1

    UniProtKB/TrEMBL
    A0A6J2D779
    Related
    ENSZCAP00025035514.1, ENSZCAT00025040088.1

  2. XM_027594902.2 → XP_027450703.1  receptor-type tyrosine-protein phosphatase O isoform X2

    UniProtKB/TrEMBL
    A0A6J2D8N9
    Related
    ENSZCAP00025035532.1, ENSZCAT00025040108.1
    Conserved Domains (3) summary
    cd00063
    Location:434 → 526
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:725 → 804
    fn3; Fibronectin type III domain
    cd14614
    Location:923 → 1167
    R-PTPc-O; catalytic domain of receptor-type tyrosine-protein phosphatase O

  3. XM_027594903.2 → XP_027450704.1  receptor-type tyrosine-protein phosphatase O isoform X3

    UniProtKB/TrEMBL
    A0A6J2D3Q0
Nucleotide Protein
Heading Accession and Version

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