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STAT3 signal transducer and activator of transcription 3 [ Puma concolor (puma) ]

Gene ID: 112853996, updated on 11-Apr-2024

Summary

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Gene symbol
STAT3
Gene description
signal transducer and activator of transcription 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Puma concolor
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Puma
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
100 current PumCon1.0 (GCF_003327715.1) Unplaced Scaffold NW_020339135.1 (2256025..2325372)

NW_020339135.1Genomic Context describing neighboring genes Neighboring gene N-acetyl-alpha-glucosaminidase Neighboring gene ATPase H+ transporting V0 subunit a1 Neighboring gene transfer RNA lysine (anticodon CUU) Neighboring gene signal transducer and activator of transcription 5A Neighboring gene signal transducer and activator of transcription 5B

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_020339135 Unplaced Scaffold Reference PumCon1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in growth hormone receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in leptin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to peptide hormone IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal transducer and activator of transcription 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Puma concolor Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference PumCon1.0 Primary Assembly

Genomic

  1. NW_020339135.1 Reference PumCon1.0 Primary Assembly

    Range
    2256025..2325372
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025917434.1 → XP_025773219.1  signal transducer and activator of transcription 3

    UniProtKB/TrEMBL
    A0A6P6HBT0
    Conserved Domains (4) summary
    cd10374
    Location:506 → 666
    SH2_STAT3; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 3 proteins
    smart00964
    Location:2 → 120
    STAT_int; STAT protein, protein interaction domain
    pfam01017
    Location:220 → 271
    STAT_alpha; STAT protein, all-alpha domain
    pfam02864
    Location:273 → 525
    STAT_bind; STAT protein, DNA binding domain
Nucleotide Protein
Heading Accession and Version

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