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ATG7 autophagy related 7 [ Piliocolobus tephrosceles (Ugandan red Colobus) ]

Gene ID: 111546916, updated on 15-Mar-2024

Summary

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Gene symbol
ATG7
Gene description
autophagy related 7
See related
Ensembl:ENSPTEG00000037675
Gene type
protein coding
RefSeq status
MODEL
Organism
Piliocolobus tephrosceles
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Piliocolobus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
23
Annotation release Status Assembly Chr Location
102 current ASM277652v3 (GCF_002776525.3) 2 NC_045435.1 (49493280..49771463, complement)
100 previous assembly ASM277652v1 (GCF_002776525.1) Unplaced Scaffold NW_019317444.1 (1116770..1395434, complement)

Chromosome 2 - NC_045435.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC111546889 Neighboring gene TAM41 mitochondrial translocator assembly and maintenance homolog Neighboring gene vestigial like family member 4 Neighboring gene uncharacterized LOC111546920 Neighboring gene uncharacterized LOC111546919 Neighboring gene uncharacterized LOC113219777 Neighboring gene mitochondrial intermembrane space import and assembly protein 40 pseudogene Neighboring gene histamine receptor H1 Neighboring gene uncharacterized LOC111546895

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Atg12 activating enzyme activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables Atg8 activating enzyme activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in C-terminal protein lipidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in autophagosome assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in autophagy of mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to nitrogen starvation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in piecemeal microautophagy of the nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein modification by small protein conjugation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in phagophore assembly site IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ubiquitin-like modifier-activating enzyme ATG7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Piliocolobus tephrosceles Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM277652v3

Genomic

  1. NC_045435.1 Reference ASM277652v3

    Range
    49493280..49771463 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_023218426.1 → XP_023074194.1  ubiquitin-like modifier-activating enzyme ATG7 isoform X3

    Conserved Domains (2) summary
    cd01486
    Location:227 → 533
    Apg7; Apg7 is an E1-like protein, that activates two different ubiquitin-like proteins, Apg12 and Apg8, and assigns them to specific E2 enzymes, Apg10 and Apg3, respectively. This leads to the covalent conjugation of Apg8 with phosphatidylethanolamine, an ...
    pfam16420
    Location:13 → 237
    ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus

  2. XM_023218421.1 → XP_023074189.1  ubiquitin-like modifier-activating enzyme ATG7 isoform X1

    UniProtKB/TrEMBL
    A0A8C9ISJ5, A0A8C9J6P4
    Conserved Domains (1) summary
    cl25654
    Location:15 → 702
    ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus

  3. XM_023218424.1 → XP_023074192.1  ubiquitin-like modifier-activating enzyme ATG7 isoform X1

    UniProtKB/TrEMBL
    A0A8C9ISJ5, A0A8C9J6P4
    Conserved Domains (1) summary
    cl25654
    Location:15 → 702
    ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus

  4. XM_023218423.1 → XP_023074191.1  ubiquitin-like modifier-activating enzyme ATG7 isoform X1

    UniProtKB/TrEMBL
    A0A8C9ISJ5, A0A8C9J6P4
    Conserved Domains (1) summary
    cl25654
    Location:15 → 702
    ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus

  5. XM_023218422.1 → XP_023074190.1  ubiquitin-like modifier-activating enzyme ATG7 isoform X1

    UniProtKB/TrEMBL
    A0A8C9ISJ5, A0A8C9J6P4
    Related
    ENSPTEP00000041011.1, ENSPTET00000054875.1
    Conserved Domains (1) summary
    cl25654
    Location:15 → 702
    ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus

  6. XM_023218428.3 → XP_023074196.1  ubiquitin-like modifier-activating enzyme ATG7 isoform X5

    Conserved Domains (2) summary
    cd01486
    Location:133 → 458
    Apg7; Apg7 is an E1-like protein, that activates two different ubiquitin-like proteins, Apg12 and Apg8, and assigns them to specific E2 enzymes, Apg10 and Apg3, respectively. This leads to the covalent conjugation of Apg8 with phosphatidylethanolamine, an ...
    pfam16420
    Location:2 → 97
    ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus

  7. XM_023218427.3 → XP_023074195.1  ubiquitin-like modifier-activating enzyme ATG7 isoform X4

    Conserved Domains (2) summary
    cd01486
    Location:162 → 487
    Apg7; Apg7 is an E1-like protein, that activates two different ubiquitin-like proteins, Apg12 and Apg8, and assigns them to specific E2 enzymes, Apg10 and Apg3, respectively. This leads to the covalent conjugation of Apg8 with phosphatidylethanolamine, an ...
    pfam16420
    Location:29 → 126
    ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus

  8. XM_023218425.1 → XP_023074193.1  ubiquitin-like modifier-activating enzyme ATG7 isoform X2

    UniProtKB/TrEMBL
    A0A8C9IWW6
    Conserved Domains (1) summary
    cl25654
    Location:15 → 650
    ATG7_N; Ubiquitin-like modifier-activating enzyme ATG7 N-terminus
Nucleotide Protein
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