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PLXNA4 plexin A4 [ Neomonachus schauinslandi (Hawaiian monk seal) ]

Gene ID: 110582759, updated on 15-Mar-2024

Summary

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Gene symbol
PLXNA4
Gene description
plexin A4
See related
EnsemblRapid:ENSNSCG00000010856
Gene type
protein coding
RefSeq status
MODEL
Organism
Neomonachus schauinslandi
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Neomonachus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 12
Exon count:
33
Annotation release Status Assembly Chr Location
101 current ASM220157v2 (GCF_002201575.2) 12 NC_058414.1 (85399248..85753233, complement)
100 previous assembly ASM220157v1 (GCF_002201575.1) Unplaced Scaffold NW_018734348.1 (20352139..20706266)

Chromosome 12 - NC_058414.1Genomic Context describing neighboring genes Neighboring gene muskelin 1 Neighboring gene podocalyxin like Neighboring gene 60S ribosomal protein L17-like Neighboring gene ribosomal protein L18-like Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 3 Neighboring gene exocyst complex component 4 Neighboring gene ATP synthase F(0) complex subunit C2, mitochondrial-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables semaphorin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in semaphorin-plexin signaling pathway involved in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of semaphorin receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
plexin-A4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Neomonachus schauinslandi Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM220157v2

Genomic

  1. NC_058414.1 Reference ASM220157v2

    Range
    85399248..85753233 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021692788.1 → XP_021548463.1  plexin-A4 isoform X2

    UniProtKB/TrEMBL
    A0A2Y9H9X6
    Related
    ENSNSCP00000013506.1, ENSNSCT00000015285.1
    Conserved Domains (8) summary
    cd11274
    Location:39 → 510
    Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
    smart00423
    Location:509 → 547
    PSI; domain found in Plexins, Semaphorins and Integrins
    cd00603
    Location:1141 → 1221
    IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
    cd01179
    Location:954 → 1037
    IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01180
    Location:857 → 952
    IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01181
    Location:1039 → 1139
    IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    pfam01437
    Location:803 → 843
    PSI; Plexin repeat
    pfam08337
    Location:1310 → 1863
    Plexin_cytopl; Plexin cytoplasmic RasGAP domain

  2. XM_021692789.1 → XP_021548464.1  plexin-A4 isoform X3

    UniProtKB/TrEMBL
    A0A2Y9HGH4
    Conserved Domains (8) summary
    cd11274
    Location:39 → 510
    Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
    smart00423
    Location:509 → 547
    PSI; domain found in Plexins, Semaphorins and Integrins
    cd00603
    Location:1141 → 1221
    IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
    cd01179
    Location:954 → 1037
    IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01180
    Location:857 → 952
    IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01181
    Location:1039 → 1139
    IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    pfam01437
    Location:803 → 843
    PSI; Plexin repeat
    pfam08337
    Location:1310 → 1859
    Plexin_cytopl; Plexin cytoplasmic RasGAP domain

  3. XM_021692787.1 → XP_021548462.1  plexin-A4 isoform X1

    UniProtKB/TrEMBL
    A0A2Y9H9W0
    Conserved Domains (8) summary
    cd11274
    Location:39 → 518
    Sema_plexin_A4; The Sema domain, a protein interacting module, of Plexin A4
    smart00423
    Location:517 → 555
    PSI; domain found in Plexins, Semaphorins and Integrins
    cd00603
    Location:1149 → 1229
    IPT_PCSR; IPT domain of Plexins and Cell Surface Receptors (PCSR) and related proteins . This subgroup contains IPT domains of plexins, receptors, like the plasminogen-related growth factor receptors, the hepatocyte growth factor-scatter factors, and the ...
    cd01179
    Location:962 → 1045
    IPT_plexin_repeat2; Second repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01180
    Location:865 → 960
    IPT_plexin_repeat1; First repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    cd01181
    Location:1047 → 1147
    IPT_plexin_repeat3; Third repeat of the IPT domain of Plexins and Cell Surface Receptors (PCSR) . Plexins are involved in the regulation of cell proliferation and of cellular adhesion and repulsion receptors. In general, there are three copies of the IPT domain present ...
    pfam01437
    Location:811 → 851
    PSI; Plexin repeat
    pfam08337
    Location:1318 → 1871
    Plexin_cytopl; Plexin cytoplasmic RasGAP domain
Nucleotide Protein
Heading Accession and Version

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