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Nbr1 NBR1 autophagy cargo receptor [ Meriones unguiculatus (Mongolian gerbil) ]

Gene ID: 110550918, updated on 15-Mar-2024

Summary

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Gene symbol
Nbr1
Gene description
NBR1 autophagy cargo receptor
See related
EnsemblRapid:ENSMUGG00015023695
Gene type
protein coding
RefSeq status
MODEL
Organism
Meriones unguiculatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Gerbillinae; Meriones
Orthologs
human mouse all
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Genomic context

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See Nbr1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2023_10 current Bangor_MerUng_6.1 (GCF_030254825.1) 7 NC_083355.1 (19909743..19939452, complement)
100 previous assembly MunDraft-v1.0 (GCF_002204375.1) Unplaced Scaffold NW_018658047.1 (64895..94876, complement)

Chromosome 7 - NC_083355.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 200 Neighboring gene transmembrane protein 106A Neighboring gene BRCA1 DNA repair associated Neighboring gene large ribosomal subunit protein eL33-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ubiquitin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in macroautophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in phagophore assembly site IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
next to BRCA1 gene 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030254825.1-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bangor_MerUng_6.1

Genomic

  1. NC_083355.1 Reference Bangor_MerUng_6.1

    Range
    19909743..19939452 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021641214.2 → XP_021496889.1  next to BRCA1 gene 1 protein isoform X1

    Conserved Domains (4) summary
    cd06396
    Location:5 → 86
    PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...
    cd02340
    Location:216 → 260
    ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...
    cd14319
    Location:930 → 968
    UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins
    pfam16158
    Location:380 → 479
    N_BRCA1_IG; Ig-like domain from next to BRCA1 gene

  2. XM_021641217.2 → XP_021496892.1  next to BRCA1 gene 1 protein isoform X4

    Related
    ENSMUGP00015034101.1, ENSMUGT00015043417.1
    Conserved Domains (3) summary
    cd06396
    Location:5 → 86
    PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...
    cd02340
    Location:216 → 260
    ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...
    pfam16158
    Location:380 → 479
    N_BRCA1_IG; Ig-like domain from next to BRCA1 gene

  3. XM_021641216.2 → XP_021496891.1  next to BRCA1 gene 1 protein isoform X3

    Related
    ENSMUGP00015034120.1, ENSMUGT00015043436.1
    Conserved Domains (4) summary
    cd06396
    Location:5 → 86
    PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...
    cd02340
    Location:216 → 260
    ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...
    cd14319
    Location:893 → 931
    UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins
    pfam16158
    Location:380 → 479
    N_BRCA1_IG; Ig-like domain from next to BRCA1 gene

  4. XM_021641215.2 → XP_021496890.1  next to BRCA1 gene 1 protein isoform X2

    Conserved Domains (4) summary
    cd06396
    Location:5 → 86
    PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...
    cd02340
    Location:205 → 249
    ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...
    cd14319
    Location:919 → 957
    UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins
    pfam16158
    Location:369 → 468
    N_BRCA1_IG; Ig-like domain from next to BRCA1 gene

  5. XM_021641212.2 → XP_021496887.1  next to BRCA1 gene 1 protein isoform X1

    Conserved Domains (4) summary
    cd06396
    Location:5 → 86
    PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...
    cd02340
    Location:216 → 260
    ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...
    cd14319
    Location:930 → 968
    UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins
    pfam16158
    Location:380 → 479
    N_BRCA1_IG; Ig-like domain from next to BRCA1 gene

  6. XM_021641211.2 → XP_021496886.1  next to BRCA1 gene 1 protein isoform X1

    Related
    ENSMUGP00015034128.1, ENSMUGT00015043444.1
    Conserved Domains (4) summary
    cd06396
    Location:5 → 86
    PB1_NBR1; The PB1 domain is an essential part of NBR1 protein, next to BRCA1, a scaffold protein mediating specific protein-protein interaction with both titin protein kinase and with another scaffold protein p62. A canonical PB1-PB1 interaction, which involves ...
    cd02340
    Location:216 → 260
    ZZ_NBR1_like; Zinc finger, ZZ type. Zinc finger present in Drosophila ref(2)P, NBR1, Human sequestosome 1 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. Drosophila ref(2)P appears ...
    cd14319
    Location:930 → 968
    UBA_NBR1; UBA domain of next to BRCA1 gene 1 protein (NBR1) and similar proteins
    pfam16158
    Location:380 → 479
    N_BRCA1_IG; Ig-like domain from next to BRCA1 gene
Nucleotide Protein Strain
Heading Accession and Version

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