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nlrc5 NLR family, CARD domain containing 5 [ Oncorhynchus mykiss (rainbow trout) ]

Gene ID: 110494725, updated on 15-Mar-2024

Summary

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Gene symbol
nlrc5
Gene description
NLR family, CARD domain containing 5
See related
Ensembl:ENSOMYG00000021005
Gene type
protein coding
RefSeq status
MODEL
Organism
Oncorhynchus mykiss
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 2
Exon count:
48
Annotation release Status Assembly Chr Location
101 current USDA_OmykA_1.1 (GCF_013265735.2) 2 NC_048566.1 (69207423..69229555, complement)
100 previous assembly Omyk_1.0 (GCF_002163495.1) 2 NC_035078.1 (53684158..53706732, complement)

Chromosome 2 - NC_048566.1Genomic Context describing neighboring genes Neighboring gene proteasome activator subunit 3 interacting protein 1 Neighboring gene copine II Neighboring gene cholesteryl ester transfer protein, plasma Neighboring gene homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MHC class I biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MHC class II biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NLR family, CARD domain containing 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oncorhynchus mykiss Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference USDA_OmykA_1.1 Primary Assembly

Genomic

  1. NC_048566.1 Reference USDA_OmykA_1.1 Primary Assembly

    Range
    69207423..69229555 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036954366.1 → XP_036810261.1  NLR family, CARD domain containing 5 isoform X4

    Conserved Domains (6) summary
    sd00033
    Location:1643 → 1670
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:1414 → 1439
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:211 → 384
    NACHT; NACHT domain
    pfam17776
    Location:525 → 644
    NLRC4_HD2; NLRC4 helical domain HD2
    pfam18461
    Location:51 → 96
    Atypical_Card; Atypical caspase recruitment domain
    cl39015
    Location:1440 → 1816
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  2. XM_036954356.1 → XP_036810251.1  NLR family, CARD domain containing 5 isoform X2

    Conserved Domains (6) summary
    sd00033
    Location:1659 → 1686
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:1430 → 1455
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:227 → 400
    NACHT; NACHT domain
    pfam17776
    Location:541 → 660
    NLRC4_HD2; NLRC4 helical domain HD2
    pfam18461
    Location:51 → 96
    Atypical_Card; Atypical caspase recruitment domain
    cl39015
    Location:1456 → 1832
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  3. XM_036954383.1 → XP_036810278.1  NLR family, CARD domain containing 5 isoform X8

    Conserved Domains (6) summary
    sd00033
    Location:1587 → 1614
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:1358 → 1383
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:228 → 401
    NACHT; NACHT domain
    pfam17776
    Location:542 → 661
    NLRC4_HD2; NLRC4 helical domain HD2
    pfam18461
    Location:51 → 96
    Atypical_Card; Atypical caspase recruitment domain
    cl39015
    Location:1384 → 1760
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  4. XM_036954368.1 → XP_036810263.1  NLR family, CARD domain containing 5 isoform X5

    UniProtKB/TrEMBL
    A0A8L0DQE5
    Related
    ENSOMYP00000131513.1, ENSOMYT00000122568.1
    Conserved Domains (6) summary
    sd00033
    Location:1632 → 1659
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:1403 → 1428
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:228 → 401
    NACHT; NACHT domain
    pfam17776
    Location:542 → 661
    NLRC4_HD2; NLRC4 helical domain HD2
    pfam18461
    Location:51 → 96
    Atypical_Card; Atypical caspase recruitment domain
    cl39015
    Location:1429 → 1805
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  5. XM_036954376.1 → XP_036810271.1  NLR family, CARD domain containing 5 isoform X7

    UniProtKB/TrEMBL
    A0A8K9UTA6
    Related
    ENSOMYP00000110505.1, ENSOMYT00000150708.1
    Conserved Domains (6) summary
    sd00033
    Location:1615 → 1642
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:1386 → 1411
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:228 → 401
    NACHT; NACHT domain
    pfam17776
    Location:542 → 661
    NLRC4_HD2; NLRC4 helical domain HD2
    pfam18461
    Location:51 → 96
    Atypical_Card; Atypical caspase recruitment domain
    cl39015
    Location:1412 → 1788
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  6. XM_036954374.1 → XP_036810269.1  NLR family, CARD domain containing 5 isoform X6

    Conserved Domains (6) summary
    sd00033
    Location:1630 → 1657
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:1401 → 1426
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:228 → 401
    NACHT; NACHT domain
    pfam17776
    Location:542 → 661
    NLRC4_HD2; NLRC4 helical domain HD2
    pfam18461
    Location:51 → 96
    Atypical_Card; Atypical caspase recruitment domain
    cl39015
    Location:1427 → 1803
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  7. XM_036954360.1 → XP_036810255.1  NLR family, CARD domain containing 5 isoform X3

    UniProtKB/TrEMBL
    A0A8C7R2A7
    Related
    ENSOMYP00000046080.2, ENSOMYT00000050135.2
    Conserved Domains (6) summary
    sd00033
    Location:1645 → 1672
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:1416 → 1441
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:228 → 401
    NACHT; NACHT domain
    pfam17776
    Location:542 → 661
    NLRC4_HD2; NLRC4 helical domain HD2
    pfam18461
    Location:51 → 96
    Atypical_Card; Atypical caspase recruitment domain
    cl39015
    Location:1442 → 1818
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  8. XM_021570046.2 → XP_021425721.2  NLR family, CARD domain containing 5 isoform X1

    UniProtKB/TrEMBL
    A0A8C7VRW9
    Related
    ENSOMYP00000046050.2, ENSOMYT00000050104.2
    Conserved Domains (6) summary
    sd00033
    Location:1660 → 1687
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:1431 → 1456
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:228 → 401
    NACHT; NACHT domain
    pfam17776
    Location:542 → 661
    NLRC4_HD2; NLRC4 helical domain HD2
    pfam18461
    Location:51 → 96
    Atypical_Card; Atypical caspase recruitment domain
    cl39015
    Location:1457 → 1833
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

  9. XM_021570054.2 → XP_021425729.2  NLR family, CARD domain containing 5 isoform X1

    UniProtKB/TrEMBL
    A0A8C7VRW9
    Conserved Domains (6) summary
    sd00033
    Location:1660 → 1687
    LRR_RI; leucine-rich repeat [structural motif]
    sd00034
    Location:1431 → 1456
    LRR_AMN1; leucine-rich repeat [structural motif]
    pfam05729
    Location:228 → 401
    NACHT; NACHT domain
    pfam17776
    Location:542 → 661
    NLRC4_HD2; NLRC4 helical domain HD2
    pfam18461
    Location:51 → 96
    Atypical_Card; Atypical caspase recruitment domain
    cl39015
    Location:1457 → 1833
    LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...

RNA

  1. XR_005037675.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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