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BCAR3 BCAR3 adaptor protein, NSP family member [ Lonchura striata (white-rumped munia) ]

Gene ID: 110468253, updated on 14-Aug-2024

Summary

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Gene symbol
BCAR3
Gene description
BCAR3 adaptor protein, NSP family member
Locus tag
RLOC_00002183
See related
Ensembl:ENSLSDG00000010998
Gene type
protein coding
RefSeq status
MODEL
Organism
Lonchura striata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Passeroidea; Estrildidae; Estrildinae; Lonchura
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 8
Exon count:
17
Annotation release Status Assembly Chr Location
101 current lonStrDom2 (GCF_005870125.1) 8 NC_042574.1 (14092597..14159982)
100 previous assembly LonStrDom1 (GCF_002197715.1) Unplaced Scaffold NW_018654728.1 (2038450..2104337)

Chromosome 8 - NC_042574.1Genomic Context describing neighboring genes Neighboring gene deoxynucleotidyltransferase terminal interacting protein 2 Neighboring gene transfer RNA arginine (anticodon UCU) Neighboring gene formin binding protein 1 like Neighboring gene down-regulator of transcription 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by GO

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphotyrosine residue binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of peptidyl-serine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in small GTPase-mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
breast cancer anti-estrogen resistance protein 3
Names
BCAR3, NSP family adaptor protein
Breast cancer anti-estrogen resistance protein 3
breast cancer anti-estrogen resistance 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Lonchura striata domestica Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference lonStrDom2 Primary Assembly

Genomic

  1. NC_042574.1 Reference lonStrDom2 Primary Assembly

    Range
    14092597..14159982
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021526025.2 → XP_021381700.2  breast cancer anti-estrogen resistance protein 3 isoform X1

    Conserved Domains (3) summary
    cd10337
    Location:217 → 352
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    pfam07647
    Location:6 → 60
    SAM_2; SAM domain (Sterile alpha motif)
    cl02485
    Location:605 → 885
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  2. XM_021525981.2 → XP_021381656.1  breast cancer anti-estrogen resistance protein 3 isoform X4

    UniProtKB/TrEMBL
    A0A218VEW8
    Related
    ENSLSDP00000015258.1
    Conserved Domains (2) summary
    cd10337
    Location:147 → 282
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:535 → 815
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  3. XM_021526008.1 → XP_021381683.1  breast cancer anti-estrogen resistance protein 3 isoform X3

    Conserved Domains (2) summary
    cd10337
    Location:39 → 174
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:427 → 707
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  4. XM_021526017.1 → XP_021381692.1  breast cancer anti-estrogen resistance protein 3 isoform X5

    Conserved Domains (2) summary
    cd10337
    Location:21 → 156
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:409 → 689
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...

  5. XM_021526001.1 → XP_021381676.1  breast cancer anti-estrogen resistance protein 3 isoform X2

    Related
    ENSLSDP00000015263.1, ENSLSDT00000017343.1
    Conserved Domains (2) summary
    cd10337
    Location:56 → 191
    SH2_BCAR3; Src homology 2 (SH2) domain in the Breast Cancer Anti-estrogen Resistance protein 3
    cl02485
    Location:444 → 724
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
Nucleotide Protein
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