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FAS Fas cell surface death receptor [ Numida meleagris (helmeted guineafowl) ]

Gene ID: 110400542, updated on 15-Mar-2024

Summary

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Gene symbol
FAS
Gene description
Fas cell surface death receptor
See related
Ensembl:ENSNMEG00000000191
Gene type
protein coding
RefSeq status
MODEL
Organism
Numida meleagris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Numididae; Numida
Orthologs
human mouse all
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Genomic context

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See FAS in Genome Data Viewer
Location:
chromosome: 5
Exon count:
9
Annotation release Status Assembly Chr Location
100 current NumMel1.0 (GCF_002078875.1) 5 NC_034413.1 (16434289..16452499, complement)

Chromosome 5 - NC_034413.1Genomic Context describing neighboring genes Neighboring gene lipase A, lysosomal acid type Neighboring gene cholesterol 25-hydroxylase Neighboring gene actin alpha 2, smooth muscle Neighboring gene STAM binding protein like 1 Neighboring gene ankyrin repeat domain 22

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034413.1 Chromosome 5 Reference NumMel1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables tumor necrosis factor receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation-induced cell death of T cells IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in extrinsic apoptotic signaling pathway in absence of ligand IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in motor neuron apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in necroptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of stress-activated MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of CD95 death-inducing signaling complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tumor necrosis factor receptor superfamily member 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Numida meleagris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NumMel1.0 Primary Assembly

Genomic

  1. NC_034413.1 Reference NumMel1.0 Primary Assembly

    Range
    16434289..16452499 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021400493.1 → XP_021256168.1  tumor necrosis factor receptor superfamily member 6 isoform X1

    Related
    ENSNMEP00000000118.1, ENSNMET00000000268.1
    Conserved Domains (3) summary
    cd00185
    Location:84 → 125
    TNFRSF; CRD2 [structural motif]
    cl14633
    Location:228 → 321
    DD; Death Domain Superfamily of protein-protein interaction domains
    cl22855
    Location:40 → 165
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

  2. XM_021400494.1 → XP_021256169.1  tumor necrosis factor receptor superfamily member 6 isoform X2

    Conserved Domains (3) summary
    cd00185
    Location:84 → 129
    TNFRSF; CRD2 [structural motif]
    cl14633
    Location:205 → 298
    DD; Death Domain Superfamily of protein-protein interaction domains
    cl22855
    Location:40 → 169
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)
Nucleotide Protein
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