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FBLN1 fibulin 1 [ Numida meleagris (helmeted guineafowl) ]

Gene ID: 110397132, updated on 15-Mar-2024

Summary

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Gene symbol
FBLN1
Gene description
fibulin 1
See related
Ensembl:ENSNMEG00000015499
Gene type
protein coding
RefSeq status
MODEL
Organism
Numida meleagris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Numididae; Numida
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
19
Annotation release Status Assembly Chr Location
100 current NumMel1.0 (GCF_002078875.1) 1 NC_034409.1 (71459819..71559894)

Chromosome 1 - NC_034409.1Genomic Context describing neighboring genes Neighboring gene structural maintenance of chromosomes 1B Neighboring gene RIB43A domain with coiled-coils 2 Neighboring gene ataxin 10 Neighboring gene uncharacterized LOC110397176

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034409.1 Chromosome 1 Reference NumMel1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables peptidase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fibulin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Numida meleagris Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NumMel1.0 Primary Assembly

Genomic

  1. NC_034409.1 Reference NumMel1.0 Primary Assembly

    Range
    71459819..71559894
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021393120.1 → XP_021248795.1  fibulin-1 isoform X3

    Conserved Domains (7) summary
    smart00179
    Location:280 → 327
    EGF_CA; Calcium-binding EGF-like domain
    cd00017
    Location:66 → 127
    ANATO; Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to ...
    cd00054
    Location:328 → 361
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07645
    Location:234 → 270
    EGF_CA; Calcium-binding EGF domain
    pfam12662
    Location:476 → 500
    cEGF; Complement Clr-like EGF-like
    pfam14670
    Location:156 → 186
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl21504
    Location:188 → 230
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

  2. XM_021393110.1 → XP_021248785.1  fibulin-1 isoform X2

    Related
    ENSNMEP00000017790.1, ENSNMET00000026313.1
    Conserved Domains (6) summary
    cd00017
    Location:95 → 156
    ANATO; Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to ...
    cd00054
    Location:357 → 390
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07645
    Location:263 → 299
    EGF_CA; Calcium-binding EGF domain
    pfam12662
    Location:197 → 220
    cEGF; Complement Clr-like EGF-like
    pfam14670
    Location:412 → 440
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl21504
    Location:217 → 259
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

  3. XM_021393099.1 → XP_021248774.1  fibulin-1 isoform X1

    Related
    ENSNMEP00000017789.1, ENSNMET00000026312.1
    Conserved Domains (6) summary
    smart00179
    Location:309 → 356
    EGF_CA; Calcium-binding EGF-like domain
    cd00017
    Location:95 → 156
    ANATO; Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to ...
    cd00054
    Location:357 → 390
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam07645
    Location:263 → 299
    EGF_CA; Calcium-binding EGF domain
    pfam12662
    Location:505 → 529
    cEGF; Complement Clr-like EGF-like
    pfam14670
    Location:185 → 215
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
Heading Accession and Version

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