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Timp3 TIMP metallopeptidase inhibitor 3 [ Mus caroli (Ryukyu mouse) ]

Gene ID: 110302929, updated on 19-Jun-2024

Summary

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Gene symbol
Timp3
Gene description
TIMP metallopeptidase inhibitor 3
See related
Ensembl:MGP_CAROLIEiJ_G0015693
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus caroli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
5
Annotation release Status Assembly Chr Location
101 current CAROLI_EIJ_v1.1 (GCF_900094665.1) 10 NC_034579.1 (80173042..80222768)

Chromosome 10 - NC_034579.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC115032154 Neighboring gene uncharacterized LOC110302930 Neighboring gene synapsin III Neighboring gene tetratricopeptide repeat protein 41 Neighboring gene heat shock protein 90 beta family member 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034579.1 Chromosome 10 Reference CAROLI_EIJ_v1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protease binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
metalloproteinase inhibitor 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mus caroli Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CAROLI_EIJ_v1.1 Primary Assembly

Genomic

  1. NC_034579.1 Reference CAROLI_EIJ_v1.1 Primary Assembly

    Range
    80173042..80222768
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021173744.1 → XP_021029403.1  metalloproteinase inhibitor 3

    UniProtKB/TrEMBL
    A0A6P5QHR3
    Related
    MGP_CAROLIEiJ_P0024355, MGP_CAROLIEiJ_T0024355.1
    Conserved Domains (1) summary
    cd03585
    Location:24 → 200
    NTR_TIMP; NTR domain, TIMP subfamily; TIMPs, or tissue inibitors of metalloproteases, are essential regulators of extracellular matrix turnover and remodeling. They form complexes with matrix metalloproteases (MMPs) and inactivate them irreversibly by ...
Nucleotide Protein
Heading Accession and Version

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