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Tcf7l2 transcription factor 7 like 2 [ Mus caroli (Ryukyu mouse) ]

Gene ID: 110285273, updated on 15-Mar-2024

Summary

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Gene symbol
Tcf7l2
Gene description
transcription factor 7 like 2
See related
Ensembl:MGP_CAROLIEiJ_G0023086
Gene type
protein coding
RefSeq status
MODEL
Organism
Mus caroli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 19
Exon count:
16
Annotation release Status Assembly Chr Location
101 current CAROLI_EIJ_v1.1 (GCF_900094665.1) 19 NC_034588.1 (52212978..52409237)

Chromosome 19 - NC_034588.1Genomic Context describing neighboring genes Neighboring gene zinc finger DHHC-type palmitoyltransferase 6 Neighboring gene vesicle transport through interaction with t-SNAREs 1A Neighboring gene uncharacterized LOC110285270 Neighboring gene uncharacterized LOC110285933 Neighboring gene small nucleolar RNA SNORA17

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_034588.1 Chromosome 19 Reference CAROLI_EIJ_v1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of beta-catenin-TCF complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of catenin-TCF7L2 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor 7-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mus caroli Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference CAROLI_EIJ_v1.1 Primary Assembly

Genomic

  1. NC_034588.1 Reference CAROLI_EIJ_v1.1 Primary Assembly

    Range
    52212978..52409237
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021151309.2 → XP_021006968.1  transcription factor 7-like 2 isoform X1

    UniProtKB/TrEMBL
    A0A6P5P3J5
    Conserved Domains (2) summary
    cd01388
    Location:353 → 420
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  2. XM_021151305.1 → XP_021006964.1  transcription factor 7-like 2 isoform X16

    UniProtKB/TrEMBL
    A0A6P5NXT2
    Conserved Domains (2) summary
    cd01388
    Location:353 → 420
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  3. XM_029472491.1 → XP_029328351.1  transcription factor 7-like 2 isoform X6

    UniProtKB/TrEMBL
    A0A6P7QRS2
    Conserved Domains (2) summary
    cd01388
    Location:353 → 420
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  4. XM_021151300.2 → XP_021006959.1  transcription factor 7-like 2 isoform X5

    UniProtKB/TrEMBL
    A0A6P5P012
    Conserved Domains (2) summary
    cd01388
    Location:353 → 420
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  5. XM_029472502.1 → XP_029328362.1  transcription factor 7-like 2 isoform X22

    UniProtKB/TrEMBL
    A0A6P7QJ22
    Conserved Domains (2) summary
    cd01388
    Location:353 → 420
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  6. XM_021151310.2 → XP_021006969.1  transcription factor 7-like 2 isoform X2

    UniProtKB/TrEMBL
    A0A6P5NXT5
    Conserved Domains (2) summary
    cd01388
    Location:349 → 416
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  7. XM_021151306.1 → XP_021006965.1  transcription factor 7-like 2 isoform X18

    UniProtKB/TrEMBL
    A0A6P5P017
    Conserved Domains (2) summary
    cd01388
    Location:349 → 416
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  8. XM_029472498.1 → XP_029328358.1  transcription factor 7-like 2 isoform X19

    UniProtKB/TrEMBL
    A0A6P7QHK1
    Conserved Domains (2) summary
    cd01388
    Location:335 → 402
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  9. XM_029472492.1 → XP_029328352.1  transcription factor 7-like 2 isoform X7

    UniProtKB/TrEMBL
    A0A6P7QJ14
    Conserved Domains (2) summary
    cd01388
    Location:335 → 402
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  10. XM_029472506.1 → XP_029328366.1  transcription factor 7-like 2 isoform X28

    UniProtKB/TrEMBL
    A0A6P7QRT6
    Related
    MGP_CAROLIEiJ_P0049166, MGP_CAROLIEiJ_T0049166.1
    Conserved Domains (2) summary
    cd01388
    Location:335 → 402
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  11. XM_029472500.1 → XP_029328360.1  transcription factor 7-like 2 isoform X20

    UniProtKB/TrEMBL
    A0A6P7QUI2
    Related
    MGP_CAROLIEiJ_P0049172, MGP_CAROLIEiJ_T0049172.1
    Conserved Domains (2) summary
    cd01388
    Location:330 → 397
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  12. XM_021151311.2 → XP_021006970.1  transcription factor 7-like 2 isoform X9

    UniProtKB/TrEMBL
    A0A6P5P022
    Related
    MGP_CAROLIEiJ_P0049161, MGP_CAROLIEiJ_T0049161.1
    Conserved Domains (2) summary
    cd01388
    Location:330 → 397
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  13. XM_021151307.2 → XP_021006966.1  transcription factor 7-like 2 isoform X25

    UniProtKB/TrEMBL
    A0A6P5P0C6
    Related
    MGP_CAROLIEiJ_P0049160, MGP_CAROLIEiJ_T0049160.1
    Conserved Domains (2) summary
    cd01388
    Location:330 → 397
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  14. XM_029472494.1 → XP_029328354.1  transcription factor 7-like 2 isoform X13

    UniProtKB/TrEMBL
    A0A6P7QP01
    Conserved Domains (2) summary
    cd01388
    Location:330 → 397
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  15. XM_021151303.2 → XP_021006962.1  transcription factor 7-like 2 isoform X12

    UniProtKB/TrEMBL
    A0A6P5P3I7
    Related
    MGP_CAROLIEiJ_P0049162, MGP_CAROLIEiJ_T0049162.1
    Conserved Domains (2) summary
    cd01388
    Location:330 → 397
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  16. XM_029472507.1 → XP_029328367.1  transcription factor 7-like 2 isoform X29

    UniProtKB/TrEMBL
    A0A6P7QJ27
    Related
    MGP_CAROLIEiJ_P0049163, MGP_CAROLIEiJ_T0049163.1
    Conserved Domains (2) summary
    cd01388
    Location:330 → 397
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  17. XM_021151313.2 → XP_021006972.1  transcription factor 7-like 2 isoform X10

    UniProtKB/TrEMBL
    A0A6P5NUV4
    Conserved Domains (2) summary
    cd01388
    Location:326 → 393
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  18. XM_021151308.2 → XP_021006967.1  transcription factor 7-like 2 isoform X26

    UniProtKB/TrEMBL
    A0A6P5NUU8
    Conserved Domains (2) summary
    cd01388
    Location:326 → 393
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  19. XM_029472505.1 → XP_029328365.1  transcription factor 7-like 2 isoform X27

    UniProtKB/TrEMBL
    A0A6P7QUI7
    Related
    MGP_CAROLIEiJ_P0049173, MGP_CAROLIEiJ_T0049173.1
    Conserved Domains (2) summary
    cd01388
    Location:326 → 393
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  20. XM_029472495.1 → XP_029328355.1  transcription factor 7-like 2 isoform X14

    UniProtKB/TrEMBL
    A0A6P7QUH7
    Conserved Domains (2) summary
    cd01388
    Location:326 → 393
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  21. XM_029472489.1 → XP_029328349.1  transcription factor 7-like 2 isoform X4

    UniProtKB/TrEMBL
    A0A6P7QNZ6
    Conserved Domains (2) summary
    cd01388
    Location:358 → 425
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  22. XM_029472488.1 → XP_029328348.1  transcription factor 7-like 2 isoform X3

    UniProtKB/TrEMBL
    A0A6P7QHJ3
    Conserved Domains (2) summary
    cd01388
    Location:358 → 425
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  23. XM_021151302.2 → XP_021006961.1  transcription factor 7-like 2 isoform X8

    UniProtKB/TrEMBL
    A0A6P5NUU1
    Conserved Domains (2) summary
    cd01388
    Location:349 → 416
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  24. XM_029472493.1 → XP_029328353.1  transcription factor 7-like 2 isoform X11

    UniProtKB/TrEMBL
    A0A6P7QHJ8
    Conserved Domains (2) summary
    cd01388
    Location:335 → 402
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  25. XM_029472497.1 → XP_029328357.1  transcription factor 7-like 2 isoform X17

    UniProtKB/TrEMBL
    A0A6P7QJ18
    Related
    MGP_CAROLIEiJ_P0049174, MGP_CAROLIEiJ_T0049174.1
    Conserved Domains (2) summary
    cd01388
    Location:358 → 425
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  26. XM_029472501.1 → XP_029328361.1  transcription factor 7-like 2 isoform X21

    UniProtKB/TrEMBL
    A0A6P7QRT2
    Related
    MGP_CAROLIEiJ_P0049164, MGP_CAROLIEiJ_T0049164.1
    Conserved Domains (2) summary
    cd01388
    Location:358 → 425
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  27. XM_029472504.1 → XP_029328364.1  transcription factor 7-like 2 isoform X24

    UniProtKB/TrEMBL
    A0A6P7QP10
    Related
    MGP_CAROLIEiJ_P0049165, MGP_CAROLIEiJ_T0049165.1
    Conserved Domains (2) summary
    cd01388
    Location:349 → 416
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding

  28. XM_029472509.1 → XP_029328369.1  transcription factor 7-like 2 isoform X30

    UniProtKB/TrEMBL
    A0A6P7QP15
    Conserved Domains (2) summary
    cd01388
    Location:326 → 393
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  29. XM_029472503.1 → XP_029328363.1  transcription factor 7-like 2 isoform X23

    UniProtKB/TrEMBL
    A0A6P7QHK5
    Conserved Domains (2) summary
    cd01388
    Location:335 → 402
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:1 → 236
    CTNNB1_binding; N-terminal CTNNB1 binding

  30. XM_029472496.1 → XP_029328356.1  transcription factor 7-like 2 isoform X15

    UniProtKB/TrEMBL
    A0A6P7QRS7
    Conserved Domains (2) summary
    cd01388
    Location:358 → 425
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:17 → 259
    CTNNB1_binding; N-terminal CTNNB1 binding
Nucleotide Protein
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