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TFEB transcription factor EB [ Pogona vitticeps (central bearded dragon) ]

Gene ID: 110080514, updated on 15-Mar-2024

Summary

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Gene symbol
TFEB
Gene description
transcription factor EB
See related
Ensembl:ENSPVIG00000010298
Gene type
protein coding
RefSeq status
MODEL
Organism
Pogona vitticeps
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Iguania; Acrodonta; Agamidae; Amphibolurinae; Pogona
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
100 current pvi1.1 (GCF_900067755.1) Unplaced Scaffold NW_018150701.1 (4718725..4799069, complement)

NW_018150701.1Genomic Context describing neighboring genes Neighboring gene forkhead box P4 Neighboring gene MyoD family inhibitor Neighboring gene gastricsin-like Neighboring gene progastricsin

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_018150701.1 Unplaced Scaffold Reference pvi1.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in humoral immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor EB

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pogona vitticeps Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference pvi1.1

Genomic

  1. NW_018150701.1 Reference pvi1.1

    Range
    4718725..4799069 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020796497.1 → XP_020652156.1  transcription factor EB

    UniProtKB/TrEMBL
    A0A6J0TUC1
    Related
    ENSPVIP00000013276.1, ENSPVIT00000016663.1
    Conserved Domains (3) summary
    cd00083
    Location:224 → 284
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:388 → 462
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:4 → 152
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus
Nucleotide Protein
Heading Accession and Version

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