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IGF1R insulin like growth factor 1 receptor [ Pogona vitticeps (central bearded dragon) ]

Gene ID: 110072986, updated on 15-Mar-2024

Summary

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Gene symbol
IGF1R
Gene description
insulin like growth factor 1 receptor
See related
Ensembl:ENSPVIG00000004357
Gene type
protein coding
RefSeq status
MODEL
Organism
Pogona vitticeps
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Iguania; Acrodonta; Agamidae; Amphibolurinae; Pogona
Orthologs
human mouse all
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Genomic context

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See IGF1R in Genome Data Viewer
Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
100 current pvi1.1 (GCF_900067755.1) Unplaced Scaffold NW_018150730.1 (3333252..3496488)

NW_018150730.1Genomic Context describing neighboring genes Neighboring gene leucine rich repeat containing 28 Neighboring gene synemin Neighboring gene pyroglutamyl-peptidase I like Neighboring gene Protein FAM169B

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_018150730.1 Unplaced Scaffold Reference pvi1.1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables insulin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables insulin receptor substrate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol 3-kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in glucose homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in insulin-like growth factor receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein autophosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of JNK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of insulin receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
insulin-like growth factor 1 receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pogona vitticeps Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference pvi1.1

Genomic

  1. NW_018150730.1 Reference pvi1.1

    Range
    3333252..3496488
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020781764.1 → XP_020637423.1  insulin-like growth factor 1 receptor isoform X1

    UniProtKB/TrEMBL
    A0A6J0SR97
    Conserved Domains (4) summary
    cd00063
    Location:831 → 920
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00757
    Location:175 → 327
    Furin-like; Furin-like cysteine rich region
    pfam01030
    Location:348 → 462
    Recep_L_domain; Receptor L domain
    cl21453
    Location:989 → 1276
    PKc_like; Protein Kinases, catalytic domain

  2. XM_020781765.1 → XP_020637424.1  insulin-like growth factor 1 receptor isoform X2

    UniProtKB/TrEMBL
    A0A6J0SUS1
    Conserved Domains (4) summary
    cd00063
    Location:831 → 920
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00757
    Location:175 → 327
    Furin-like; Furin-like cysteine rich region
    pfam01030
    Location:348 → 462
    Recep_L_domain; Receptor L domain
    cl21453
    Location:988 → 1275
    PKc_like; Protein Kinases, catalytic domain

  3. XM_020781766.1 → XP_020637425.1  insulin-like growth factor 1 receptor isoform X3

    UniProtKB/TrEMBL
    A0A6J0SR94
    Related
    ENSPVIP00000005366.1, ENSPVIT00000006852.1
    Conserved Domains (4) summary
    cd00063
    Location:816 → 905
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00757
    Location:160 → 312
    Furin-like; Furin-like cysteine rich region
    pfam01030
    Location:333 → 447
    Recep_L_domain; Receptor L domain
    cl21453
    Location:974 → 1261
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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