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lrp2a low density lipoprotein receptor-related protein 2a [ Oncorhynchus kisutch (coho salmon) ]

Gene ID: 109871228, updated on 14-Mar-2024

Summary

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Gene symbol
lrp2a
Gene description
low density lipoprotein receptor-related protein 2a
See related
Ensembl:ENSOKIG00005043132
Gene type
protein coding
RefSeq status
MODEL
Organism
Oncorhynchus kisutch
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Protacanthopterygii; Salmoniformes; Salmonidae; Salmoninae; Oncorhynchus
Also known as
lrp2
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: LG26
Exon count:
82
Annotation release Status Assembly LG Location
101 current Okis_V2 (GCF_002021735.2) LG26 NC_034199.2 (13526495..13599932, complement)
100 previous assembly Okis_V1 (GCF_002021735.1) LG26 NC_034199.1 (13119268..13200720)

Linkage Group LG26 - NC_034199.2Genomic Context describing neighboring genes Neighboring gene dehydrogenase/reductase (SDR family) member 9 Neighboring gene retinol dehydrogenase 1 Neighboring gene coiled-coil domain-containing protein 89 Neighboring gene collagen, type XXVIII, alpha 2a

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Multi-tissue transcriptome profiles for coho salmon (Oncorhynchus kisutch), a species undergoing rediploidization following whole-genome duplication. Kim JH, et al. Mar Genomics, 2016 Feb. PMID 26614614

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
low-density lipoprotein receptor-related protein 2
Names
LDL receptor related protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Oncorhynchus kisutch Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Okis_V2 Primary Assembly

Genomic

  1. NC_034199.2 Reference Okis_V2 Primary Assembly

    Range
    13526495..13599932 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031806040.1 → XP_031661900.1  low-density lipoprotein receptor-related protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A8C7KBT3
    Related
    ENSOKIP00005101574.1, ENSOKIT00005108848.1
    Conserved Domains (12) summary
    smart00192
    Location:2918 → 2950
    LDLa; Low-density lipoprotein receptor domain class A
    smart00135
    Location:2559 → 2599
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00179
    Location:1404 → 1434
    EGF_CA; Calcium-binding EGF-like domain
    COG3391
    Location:421 → 593
    YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
    cd00112
    Location:1117 → 1151
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd05819
    Location:1794 → 1831
    NHL; NHL repeat [structural motif]
    pfam00058
    Location:4209 → 4249
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    cl18310
    Location:1786 → 1993
    NHL; NHL repeat unit of beta-propeller proteins
    pfam07645
    Location:3165 → 3204
    EGF_CA; Calcium-binding EGF domain
    pfam14670
    Location:2036 → 2072
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00104
    Location:2833 → 2867
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cl39070
    Location:2617 → 2647
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B

  2. XM_031806038.1 → XP_031661898.1  low-density lipoprotein receptor-related protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A8C7KBT3
    Conserved Domains (12) summary
    smart00192
    Location:2940 → 2972
    LDLa; Low-density lipoprotein receptor domain class A
    smart00135
    Location:2559 → 2599
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00179
    Location:1404 → 1434
    EGF_CA; Calcium-binding EGF-like domain
    COG3391
    Location:421 → 593
    YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
    cd00112
    Location:1117 → 1151
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd05819
    Location:1794 → 1831
    NHL; NHL repeat [structural motif]
    pfam00058
    Location:4231 → 4271
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    cl18310
    Location:1786 → 1993
    NHL; NHL repeat unit of beta-propeller proteins
    pfam07645
    Location:3187 → 3226
    EGF_CA; Calcium-binding EGF domain
    pfam14670
    Location:2036 → 2072
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00104
    Location:2855 → 2889
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cl39070
    Location:2617 → 2647
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B

  3. XM_031806039.1 → XP_031661899.1  low-density lipoprotein receptor-related protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A8C7KBT3
    Conserved Domains (12) summary
    smart00192
    Location:2925 → 2957
    LDLa; Low-density lipoprotein receptor domain class A
    smart00135
    Location:2566 → 2606
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00179
    Location:1411 → 1441
    EGF_CA; Calcium-binding EGF-like domain
    COG3391
    Location:421 → 593
    YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
    cd00112
    Location:1117 → 1151
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd05819
    Location:1801 → 1838
    NHL; NHL repeat [structural motif]
    pfam00058
    Location:4216 → 4256
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    cl18310
    Location:1793 → 2000
    NHL; NHL repeat unit of beta-propeller proteins
    pfam07645
    Location:3172 → 3211
    EGF_CA; Calcium-binding EGF domain
    pfam14670
    Location:2043 → 2079
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00104
    Location:2840 → 2874
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cl39070
    Location:2624 → 2654
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B

  4. XM_031806037.1 → XP_031661897.1  low-density lipoprotein receptor-related protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8C7KBT3
    Conserved Domains (12) summary
    smart00192
    Location:2947 → 2979
    LDLa; Low-density lipoprotein receptor domain class A
    smart00135
    Location:2566 → 2606
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00179
    Location:1411 → 1441
    EGF_CA; Calcium-binding EGF-like domain
    COG3391
    Location:421 → 593
    YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
    cd00112
    Location:1117 → 1151
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd05819
    Location:1801 → 1838
    NHL; NHL repeat [structural motif]
    pfam00058
    Location:4238 → 4278
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    cl18310
    Location:1793 → 2000
    NHL; NHL repeat unit of beta-propeller proteins
    pfam07645
    Location:3194 → 3233
    EGF_CA; Calcium-binding EGF domain
    pfam14670
    Location:2043 → 2079
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00104
    Location:2862 → 2896
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cl39070
    Location:2624 → 2654
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B

  5. XM_031806036.1 → XP_031661896.1  low-density lipoprotein receptor-related protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8C7KBT3
    Conserved Domains (12) summary
    smart00192
    Location:2947 → 2979
    LDLa; Low-density lipoprotein receptor domain class A
    smart00135
    Location:2566 → 2606
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00179
    Location:1411 → 1441
    EGF_CA; Calcium-binding EGF-like domain
    COG3391
    Location:421 → 593
    YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
    cd00112
    Location:1117 → 1151
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd05819
    Location:1801 → 1838
    NHL; NHL repeat [structural motif]
    pfam00058
    Location:4238 → 4278
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    cl18310
    Location:1793 → 2000
    NHL; NHL repeat unit of beta-propeller proteins
    pfam07645
    Location:3194 → 3233
    EGF_CA; Calcium-binding EGF domain
    pfam14670
    Location:2043 → 2079
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00104
    Location:2862 → 2896
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cl39070
    Location:2624 → 2654
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
Nucleotide Protein
Heading Accession and Version

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