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Notch1 notch receptor 1 [ Castor canadensis (American beaver) ]

Gene ID: 109698981, updated on 14-Mar-2024

Summary

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Gene symbol
Notch1
Gene description
notch receptor 1
See related
Ensembl:ENSCCNG00000006513
Gene type
protein coding
RefSeq status
MODEL
Organism
Castor canadensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Castoridae; Castor
Orthologs
human mouse all
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Genomic context

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See Notch1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
34
Annotation release Status Assembly Chr Location
100 current C.can genome v1.0 (GCF_001984765.1) Unplaced Scaffold NW_017872414.1 (14229..58806, complement)

NW_017872414.1Genomic Context describing neighboring genes Neighboring gene EGF like domain multiple 7 Neighboring gene 1-acylglycerol-3-phosphate O-acyltransferase 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_017872414.1 Unplaced Scaffold Reference C.can genome v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De Novo Genome and Transcriptome Assembly of the Canadian Beaver (Castor canadensis). Lok S, et al. G3 (Bethesda), 2017 Feb 9. PMID 28087693, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of developmental process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neurogenic locus notch homolog protein 1
Names
neurogenic locus notch protein 1
notch 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Castor canadensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference C.can genome v1.0

Genomic

  1. NW_017872414.1 Reference C.can genome v1.0

    Range
    14229..58806 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020183444.1 → XP_020039033.1  neurogenic locus notch homolog protein 1

    UniProtKB/TrEMBL
    A0A250YMC4, A0A8C0ZNH2
    Related
    ENSCCNP00000006173.1, ENSCCNT00000008103.1
    Conserved Domains (10) summary
    smart00004
    Location:1442 → 1479
    NL; Domain found in Notch and Lin-12
    cd00054
    Location:869 → 905
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00204
    Location:1922 → 2034
    ANK; ankyrin repeats; ankyrin repeats mediate protein-protein interactions in very diverse families of proteins. The number of ANK repeats in a protein can range from 2 to over 20 (ankyrins, for example). ANK repeats may occur in combinations with other ...
    sd00045
    Location:1880 → 1925
    ANK; ANK repeat [structural motif]
    pfam00066
    Location:1488 → 1522
    Notch; LNR domain
    pfam06816
    Location:1567 → 1618
    NOD; NOTCH protein
    pfam07684
    Location:1672 → 1729
    NODP; NOTCH protein
    pfam11936
    Location:2478 → 2538
    DUF3454; Domain of unknown function (DUF3454)
    pfam12796
    Location:1873 → 1958
    Ank_2; Ankyrin repeats (3 copies)
    cl26464
    Location:2214 → 2515
    Atrophin-1; Atrophin-1 family

RNA

  1. XR_002213590.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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