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Pkd2 polycystin 2, transient receptor potential cation channel [ Castor canadensis (American beaver) ]

Gene ID: 109679388, updated on 14-Mar-2024

Summary

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Gene symbol
Pkd2
Gene description
polycystin 2, transient receptor potential cation channel
Gene type
protein coding
RefSeq status
MODEL
Organism
Castor canadensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Castoridae; Castor
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
100 current C.can genome v1.0 (GCF_001984765.1) Unplaced Scaffold NW_017887068.1 (7121..56996)

NW_017887068.1Genomic Context describing neighboring genes Neighboring gene ATP-binding cassette sub-family G member 3-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_017887068.1 Unplaced Scaffold Reference C.can genome v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables muscle alpha-actinin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated calcium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables voltage-gated sodium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in detection of mechanical stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in potassium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in release of sequestered calcium ion into cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: polycystin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Castor canadensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference C.can genome v1.0

Genomic

  1. NW_017887068.1 Reference C.can genome v1.0

    Range
    7121..56996
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020154614.1 → XP_020010203.1  LOW QUALITY PROTEIN: polycystin-2

    UniProtKB/TrEMBL
    A0A8B7TRM5
    Conserved Domains (2) summary
    pfam08016
    Location:259 → 677
    PKD_channel; Polycystin cation channel
    cl08302
    Location:722 → 768
    EFh; EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
Nucleotide Protein
Heading Accession and Version

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