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POT1 protection of telomeres 1 [ Manis javanica (Malayan pangolin) ]

Gene ID: 108386679, updated on 18-Sep-2024

Summary

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Gene symbol
POT1
Gene description
protection of telomeres 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Manis javanica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Pholidota; Manidae; Manis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
101 current YNU_ManJav_2.0 (GCF_014570535.1) Unplaced Scaffold NW_023436089.1 (2928589..3058652)
100 previous assembly ManJav1.0 (GCF_001685135.1) Unplaced Scaffold NW_016561370.1 (128291..208282, complement)

NW_023436089.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene developmentally-regulated GTP-binding protein 1-like Neighboring gene G protein-coupled receptor 37 Neighboring gene transmembrane protein 229A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G-rich strand telomeric DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomerase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of telomere maintenance via telomerase IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomere capping IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome, telomeric region IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of nuclear telomere cap complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protection of telomeres protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Manis javanica Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference YNU_ManJav_2.0 Primary Assembly

Genomic

  1. NW_023436089.1 Reference YNU_ManJav_2.0 Primary Assembly

    Range
    2928589..3058652
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037023491.1 → XP_036879386.1  protection of telomeres protein 1 isoform X4

    Conserved Domains (3) summary
    smart00976
    Location:158 → 288
    Telo_bind; Telomeric single stranded DNA binding POT1/CDC13
    cd20374
    Location:493 → 752
    Pot1C; Protection Of Telomeres Protein 1 (POT1) C-terminal region
    pfam16686
    Location:300 → 446
    POT1PC; ssDNA-binding domain of telomere protection protein

  2. XM_037023488.1 → XP_036879383.1  protection of telomeres protein 1 isoform X1

    Conserved Domains (3) summary
    smart00976
    Location:158 → 288
    Telo_bind; Telomeric single stranded DNA binding POT1/CDC13
    cd20374
    Location:493 → 752
    Pot1C; Protection Of Telomeres Protein 1 (POT1) C-terminal region
    pfam16686
    Location:300 → 446
    POT1PC; ssDNA-binding domain of telomere protection protein

  3. XM_037023490.1 → XP_036879385.1  protection of telomeres protein 1 isoform X3

    Conserved Domains (3) summary
    smart00976
    Location:142 → 272
    Telo_bind; Telomeric single stranded DNA binding POT1/CDC13
    cd20374
    Location:477 → 736
    Pot1C; Protection Of Telomeres Protein 1 (POT1) C-terminal region
    pfam16686
    Location:284 → 430
    POT1PC; ssDNA-binding domain of telomere protection protein

  4. XM_017644669.2 → XP_017500158.2  protection of telomeres protein 1 isoform X2

    Conserved Domains (3) summary
    smart00976
    Location:158 → 288
    Telo_bind; Telomeric single stranded DNA binding POT1/CDC13
    cd20374
    Location:493 → 779
    Pot1C; Protection Of Telomeres Protein 1 (POT1) C-terminal region
    pfam16686
    Location:300 → 446
    POT1PC; ssDNA-binding domain of telomere protection protein

  5. XM_037023489.1 → XP_036879384.1  protection of telomeres protein 1 isoform X1

    Conserved Domains (3) summary
    smart00976
    Location:158 → 288
    Telo_bind; Telomeric single stranded DNA binding POT1/CDC13
    cd20374
    Location:493 → 752
    Pot1C; Protection Of Telomeres Protein 1 (POT1) C-terminal region
    pfam16686
    Location:300 → 446
    POT1PC; ssDNA-binding domain of telomere protection protein
Nucleotide Protein
Heading Accession and Version

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