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ANK2 ankyrin 2 [ Manis javanica (Malayan pangolin) ]

Gene ID: 108383769, updated on 14-Mar-2024

Summary

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Gene symbol
ANK2
Gene description
ankyrin 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Manis javanica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Pholidota; Manidae; Manis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
55
Annotation release Status Assembly Chr Location
101 current YNU_ManJav_2.0 (GCF_014570535.1) Unplaced Scaffold NW_023436210.1 (4941839..5306890, complement)
100 previous assembly ManJav1.0 (GCF_001685135.1) Unplaced Scaffold NW_016550062.1 (1420..81277, complement)

NW_023436210.1Genomic Context describing neighboring genes Neighboring gene group XIIB secretory phospholipase A2-like protein Neighboring gene calcium/calmodulin dependent protein kinase II delta Neighboring gene RNA-binding protein 42-like Neighboring gene E3 ubiquitin-protein ligase MARCHF11-like Neighboring gene 40S ribosomal protein S23-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein localization to T-tubule IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cardiac muscle contraction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in T-tubule IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ankyrin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Manis javanica Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference YNU_ManJav_2.0 Primary Assembly

Genomic

  1. NW_023436210.1 Reference YNU_ManJav_2.0 Primary Assembly

    Range
    4941839..5306890 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037001140.1 → XP_036857035.1  ankyrin-2 isoform X2

    Conserved Domains (7) summary
    smart00218
    Location:966 → 1070
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA03095
    Location:404 → 689
    PHA03095; ankyrin-like protein; Provisional
    cd08804
    Location:1449 → 1532
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:430 → 461
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:761 → 813
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1291 → 1420
    UPA_2; UPA domain
    cl39094
    Location:561 → 785
    Ank_2; Ankyrin repeats (3 copies)

  2. XM_037001150.1 → XP_036857045.1  ankyrin-2 isoform X11

    Conserved Domains (8) summary
    smart00218
    Location:899 → 1003
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02876
    Location:248 → 588
    PHA02876; ankyrin repeat protein; Provisional
    PHA03095
    Location:27 → 356
    PHA03095; ankyrin-like protein; Provisional
    cd08804
    Location:1382 → 1465
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:628 → 659
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:695 → 747
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1224 → 1353
    UPA_2; UPA domain
    cl39094
    Location:495 → 719
    Ank_2; Ankyrin repeats (3 copies)

  3. XM_037001145.1 → XP_036857040.1  ankyrin-2 isoform X7

    Conserved Domains (7) summary
    smart00218
    Location:966 → 1070
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA03095
    Location:404 → 689
    PHA03095; ankyrin-like protein; Provisional
    cd08804
    Location:1449 → 1532
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:430 → 461
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:761 → 813
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1291 → 1420
    UPA_2; UPA domain
    cl39094
    Location:561 → 785
    Ank_2; Ankyrin repeats (3 copies)

  4. XM_037001146.1 → XP_036857041.1  ankyrin-2 isoform X8

    Conserved Domains (7) summary
    smart00218
    Location:965 → 1069
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA03095
    Location:404 → 689
    PHA03095; ankyrin-like protein; Provisional
    cd08804
    Location:1448 → 1531
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:430 → 461
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:761 → 813
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1290 → 1419
    UPA_2; UPA domain
    cl39094
    Location:561 → 785
    Ank_2; Ankyrin repeats (3 copies)

  5. XM_037001139.1 → XP_036857034.1  ankyrin-2 isoform X1

    Conserved Domains (9) summary
    smart00218
    Location:1015 → 1152
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00449
    Location:2272 → 2630
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:419 → 704
    PHA03095; ankyrin-like protein; Provisional
    cd08804
    Location:3600 → 3683
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:445 → 476
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:776 → 828
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1373 → 1502
    UPA_2; UPA domain
    NF033804
    Location:1884 → 2030
    Streccoc_I_II; antigen I/II family LPXTG-anchored adhesin
    cl39094
    Location:576 → 800
    Ank_2; Ankyrin repeats (3 copies)

  6. XM_037001141.1 → XP_036857036.1  ankyrin-2 isoform X3

    Conserved Domains (7) summary
    smart00218
    Location:992 → 1096
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA03095
    Location:419 → 704
    PHA03095; ankyrin-like protein; Provisional
    cd08804
    Location:1475 → 1558
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:445 → 476
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:776 → 828
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1317 → 1446
    UPA_2; UPA domain
    cl39094
    Location:576 → 800
    Ank_2; Ankyrin repeats (3 copies)

  7. XM_037001153.1 → XP_036857048.1  ankyrin-2 isoform X14

    Conserved Domains (11) summary
    smart00218
    Location:1005 → 1142
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00121
    Location:1572 → 1940
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:2262 → 2620
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:413 → 698
    PHA03095; ankyrin-like protein; Provisional
    COG0666
    Location:45 → 179
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd08804
    Location:3590 → 3673
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:439 → 470
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:770 → 822
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1363 → 1492
    UPA_2; UPA domain
    NF033804
    Location:1874 → 2020
    Streccoc_I_II; antigen I/II family LPXTG-anchored adhesin
    cl39094
    Location:570 → 794
    Ank_2; Ankyrin repeats (3 copies)

  8. XM_037001152.1 → XP_036857047.1  ankyrin-2 isoform X13

    Conserved Domains (10) summary
    smart00218
    Location:1013 → 1150
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PTZ00121
    Location:1580 → 1948
    PTZ00121; MAEBL; Provisional
    PTZ00449
    Location:2270 → 2628
    PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
    PHA03095
    Location:421 → 706
    PHA03095; ankyrin-like protein; Provisional
    cd08804
    Location:3598 → 3681
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:447 → 478
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:778 → 830
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1371 → 1500
    UPA_2; UPA domain
    NF033804
    Location:1882 → 2028
    Streccoc_I_II; antigen I/II family LPXTG-anchored adhesin
    cl39094
    Location:578 → 802
    Ank_2; Ankyrin repeats (3 copies)

  9. XM_037001143.1 → XP_036857038.1  ankyrin-2 isoform X5

    Conserved Domains (8) summary
    smart00218
    Location:942 → 1046
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    COG0666
    Location:45 → 179
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd08804
    Location:1425 → 1508
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:439 → 470
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:737 → 789
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1267 → 1396
    UPA_2; UPA domain
    pfam12796
    Location:411 → 502
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:486 → 761
    Ank_2; Ankyrin repeats (3 copies)

  10. XM_037001151.1 → XP_036857046.1  ankyrin-2 isoform X12

    Conserved Domains (8) summary
    smart00218
    Location:876 → 980
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA03095
    Location:152 → 470
    PHA03095; ankyrin-like protein; Provisional
    cd08804
    Location:1359 → 1442
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:604 → 635
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:671 → 723
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1201 → 1330
    UPA_2; UPA domain
    pfam12796
    Location:85 → 172
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:420 → 695
    Ank_2; Ankyrin repeats (3 copies)

  11. XM_037001149.1 → XP_036857044.1  ankyrin-2 isoform X10

    Conserved Domains (8) summary
    smart00218
    Location:909 → 1013
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA02876
    Location:257 → 597
    PHA02876; ankyrin repeat protein; Provisional
    PHA03095
    Location:46 → 365
    PHA03095; ankyrin-like protein; Provisional
    cd08804
    Location:1392 → 1475
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:637 → 668
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:704 → 756
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1234 → 1363
    UPA_2; UPA domain
    cl39094
    Location:504 → 728
    Ank_2; Ankyrin repeats (3 copies)

  12. XM_037001148.1 → XP_036857043.1  ankyrin-2 isoform X9

    Conserved Domains (8) summary
    smart00218
    Location:942 → 1046
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    COG0666
    Location:45 → 179
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd08804
    Location:1425 → 1508
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:439 → 470
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:737 → 789
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1267 → 1396
    UPA_2; UPA domain
    pfam12796
    Location:411 → 502
    Ank_2; Ankyrin repeats (3 copies)
    cl39094
    Location:486 → 761
    Ank_2; Ankyrin repeats (3 copies)

  13. XM_037001144.1 → XP_036857039.1  ankyrin-2 isoform X6

    Conserved Domains (8) summary
    smart00218
    Location:970 → 1074
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA03095
    Location:413 → 698
    PHA03095; ankyrin-like protein; Provisional
    COG0666
    Location:45 → 179
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd08804
    Location:1453 → 1536
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:439 → 470
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:770 → 822
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1295 → 1424
    UPA_2; UPA domain
    cl39094
    Location:570 → 794
    Ank_2; Ankyrin repeats (3 copies)

  14. XM_037001142.1 → XP_036857037.1  ankyrin-2 isoform X4

    Conserved Domains (8) summary
    smart00218
    Location:975 → 1079
    ZU5; Domain present in ZO-1 and Unc5-like netrin receptors
    PHA03095
    Location:413 → 698
    PHA03095; ankyrin-like protein; Provisional
    COG0666
    Location:45 → 179
    ANKYR; Ankyrin repeat [Signal transduction mechanisms]
    cd08804
    Location:1458 → 1541
    Death_ank2; Death domain of Ankyrin-2
    sd00045
    Location:439 → 470
    ANK; ANK repeat [structural motif]
    pfam13637
    Location:770 → 822
    Ank_4; Ankyrin repeats (many copies)
    pfam17809
    Location:1300 → 1429
    UPA_2; UPA domain
    cl39094
    Location:570 → 794
    Ank_2; Ankyrin repeats (3 copies)
Nucleotide Protein
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