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PCLO piccolo presynaptic cytomatrix protein [ Cebus imitator (Panamanian white-faced capuchin) ]

Gene ID: 108300334, updated on 14-Mar-2024

Summary

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Gene symbol
PCLO
Gene description
piccolo presynaptic cytomatrix protein
See related
Ensembl:ENSCCAG00000035496
Gene type
protein coding
RefSeq status
MODEL
Organism
Cebus imitator
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Cebidae; Cebinae; Cebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
28
Annotation release Status Assembly Chr Location
101 current Cebus_imitator-1.0 (GCF_001604975.1) Unplaced Scaffold NW_016107341.1 (3938073..4347344)

NW_016107341.1Genomic Context describing neighboring genes Neighboring gene semaphorin 3E Neighboring gene DNA (cytosine-5)-methyltransferase 1-like Neighboring gene U1 spliceosomal RNA Neighboring gene prothymosin alpha-like Neighboring gene bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial-like Neighboring gene calcium voltage-gated channel auxiliary subunit alpha2delta 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_016107341 Unplaced Scaffold Reference Cebus_imitator-1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural constituent of presynaptic active zone IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in presynaptic active zone assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein localization to synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in GABA-ergic synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoskeleton of presynaptic active zone IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein piccolo

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cebus imitator Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cebus_imitator-1.0

Genomic

  1. NW_016107341.1 Reference Cebus_imitator-1.0

    Range
    3938073..4347344
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037736537.1 → XP_037592465.1  protein piccolo isoform X1

    Conserved Domains (8) summary
    PTZ00121
    Location:1129 → 1679
    PTZ00121; MAEBL; Provisional
    cd04031
    Location:4674 → 4806
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03247
    Location:210 → 565
    PHA03247; large tegument protein UL36; Provisional
    PRK10263
    Location:3550 → 3945
    PRK10263; DNA translocase FtsK; Provisional
    cd00992
    Location:4476 → 4567
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15774
    Location:567 → 628
    FYVE1_PCLO; FYVE-related domain 1 found in protein piccolo
    pfam00168
    Location:5066 → 5175
    C2; C2 domain
    pfam05715
    Location:1037 → 1095
    zf-piccolo; Piccolo Zn-finger

  2. XM_037736540.1 → XP_037592468.1  protein piccolo isoform X3

    Conserved Domains (8) summary
    PTZ00121
    Location:1129 → 1679
    PTZ00121; MAEBL; Provisional
    cd04031
    Location:4674 → 4806
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03247
    Location:210 → 565
    PHA03247; large tegument protein UL36; Provisional
    PRK10263
    Location:3550 → 3945
    PRK10263; DNA translocase FtsK; Provisional
    cd00992
    Location:4476 → 4567
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15774
    Location:567 → 628
    FYVE1_PCLO; FYVE-related domain 1 found in protein piccolo
    pfam00168
    Location:5030 → 5139
    C2; C2 domain
    pfam05715
    Location:1037 → 1095
    zf-piccolo; Piccolo Zn-finger

  3. XM_017523093.2 → XP_017378582.1  protein piccolo isoform X4

    UniProtKB/TrEMBL
    A0A2K5S465
    Related
    ENSCCAP00000035171.1, ENSCCAT00000052948.1

  4. XM_037736538.1 → XP_037592466.1  protein piccolo isoform X2

    Conserved Domains (8) summary
    PTZ00121
    Location:1129 → 1679
    PTZ00121; MAEBL; Provisional
    cd04031
    Location:4674 → 4797
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03247
    Location:210 → 565
    PHA03247; large tegument protein UL36; Provisional
    PRK10263
    Location:3550 → 3945
    PRK10263; DNA translocase FtsK; Provisional
    cd00992
    Location:4476 → 4567
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15774
    Location:567 → 628
    FYVE1_PCLO; FYVE-related domain 1 found in protein piccolo
    pfam00168
    Location:5057 → 5166
    C2; C2 domain
    pfam05715
    Location:1037 → 1095
    zf-piccolo; Piccolo Zn-finger

  5. XM_037736541.1 → XP_037592469.1  protein piccolo isoform X5

    Conserved Domains (8) summary
    PTZ00121
    Location:1129 → 1679
    PTZ00121; MAEBL; Provisional
    cd04031
    Location:4516 → 4648
    C2A_RIM1alpha; C2 domain first repeat contained in Rab3-interacting molecule (RIM) proteins
    PHA03247
    Location:210 → 565
    PHA03247; large tegument protein UL36; Provisional
    PRK01741
    Location:3665 → 3807
    PRK01741; cell division protein ZipA; Provisional
    cd00992
    Location:4318 → 4409
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd15774
    Location:567 → 628
    FYVE1_PCLO; FYVE-related domain 1 found in protein piccolo
    pfam00168
    Location:4908 → 5017
    C2; C2 domain
    pfam05715
    Location:1037 → 1095
    zf-piccolo; Piccolo Zn-finger

  6. XM_017523096.2 → XP_017378585.1  protein piccolo isoform X6

RNA

  1. XR_005199165.1 RNA Sequence

  2. XR_005199164.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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