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ERBB4 erb-b2 receptor tyrosine kinase 4 [ Miniopterus natalensis ]

Gene ID: 107524731, updated on 11-Apr-2024

Summary

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Gene symbol
ERBB4
Gene description
erb-b2 receptor tyrosine kinase 4
Gene type
protein coding
RefSeq status
MODEL
Organism
Miniopterus natalensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Chiroptera; Yangochiroptera; Miniopteridae; Miniopterus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
28
Annotation release Status Assembly Chr Location
100 current Mnat.v1 (GCF_001595765.1) Unplaced Scaffold NW_015504237.1 (5080480..5891637, complement)

NW_015504237.1Genomic Context describing neighboring genes Neighboring gene 60S ribosomal protein L9 pseudogene Neighboring gene proteasome subunit alpha type-1 pseudogene Neighboring gene PC-esterase domain-containing protein 1B-like Neighboring gene IKAROS family zinc finger 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015504237.1 Unplaced Scaffold Reference Mnat.v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables epidermal growth factor receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in basal plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
receptor tyrosine-protein kinase erbB-4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Miniopterus natalensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnat.v1

Genomic

  1. NW_015504237.1 Reference Mnat.v1

    Range
    5080480..5891637 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016196749.1 → XP_016052235.1  receptor tyrosine-protein kinase erbB-4

    Conserved Domains (8) summary
    cd05110
    Location:710 → 1012
    PTKc_HER4; Catalytic domain of the Protein Tyrosine Kinase, HER4
    cd12092
    Location:642 → 685
    TM_ErbB4; Transmembrane domain of ErbB4, a Protein Tyrosine Kinase
    smart00261
    Location:549 → 596
    FU; Furin-like repeats
    cd00064
    Location:229 → 274
    FU; Furin-like repeats. Cysteine rich region. Exact function of the domain is not known. Furin is a serine-kinase dependent proprotein processor. Other members of this family include endoproteases and cell surface receptors.
    pfam00757
    Location:186 → 332
    Furin-like; Furin-like cysteine rich region
    pfam01030
    Location:55 → 167
    Recep_L_domain; Receptor L domain
    pfam07714
    Location:718 → 974
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14843
    Location:502 → 634
    GF_recep_IV; Growth factor receptor domain IV
Nucleotide Protein
Heading Accession and Version

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