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TCF7L2 transcription factor 7 like 2 [ Parus major (Great Tit) ]

Gene ID: 107206579, updated on 3-Aug-2024

Summary

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Gene symbol
TCF7L2
Gene description
transcription factor 7 like 2
See related
Ensembl:ENSPMJG00000005275
Gene type
protein coding
RefSeq status
MODEL
Organism
Parus major
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Paridae; Parus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 6
Exon count:
15
Annotation release Status Assembly Chr Location
102 current Parus_major1.1 (GCF_001522545.3) 6 NC_031775.1 (25738847..25850278)
100 previous assembly Parus_major1.0.3 (GCF_001522545.1) 6 NC_029275.1 (24708885..24844181)

Chromosome 6 - NC_031775.1Genomic Context describing neighboring genes Neighboring gene zinc finger DHHC-type palmitoyltransferase 6 Neighboring gene vesicle transport through interaction with t-SNAREs 1A Neighboring gene hyaluronan binding protein 2 Neighboring gene nebulin related anchoring protein Neighboring gene caspase 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of beta-catenin-TCF complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of catenin-TCF7L2 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
transcription factor 7-like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Parus major Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Parus_major1.1 Primary Assembly

Genomic

  1. NC_031775.1 Reference Parus_major1.1 Primary Assembly

    Range
    25738847..25850278
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019007299.2 → XP_018862844.1  transcription factor 7-like 2 isoform X1

    Related
    ENSPMJP00000006266.1, ENSPMJT00000008776.1

  2. XM_033515671.1 → XP_033371562.1  transcription factor 7-like 2 isoform X4

    Related
    ENSPMJP00000006277.1, ENSPMJT00000008787.1
    Conserved Domains (2) summary
    cd01388
    Location:200 → 267
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:26 → 106
    CTNNB1_binding; N-terminal CTNNB1 binding

  3. XM_033515670.1 → XP_033371561.1  transcription factor 7-like 2 isoform X2

    Conserved Domains (2) summary
    cd01388
    Location:175 → 242
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:2 → 76
    CTNNB1_binding; N-terminal CTNNB1 binding

  4. XM_019007303.2 → XP_018862848.1  transcription factor 7-like 2 isoform X3

    Conserved Domains (2) summary
    cd01388
    Location:175 → 242
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:2 → 76
    CTNNB1_binding; N-terminal CTNNB1 binding

  5. XM_019007298.2 → XP_018862843.2  transcription factor 7-like 2 isoform X5

    Conserved Domains (2) summary
    cd01388
    Location:210 → 277
    SOX-TCF_HMG-box; class I member of the HMG-box superfamily of DNA-binding proteins. These proteins contain a single HMG box, and bind the minor groove of DNA in a highly sequence-specific manner. Members include SRY and its homologs in insects and vertebrates, and ...
    pfam08347
    Location:42 → 116
    CTNNB1_binding; N-terminal CTNNB1 binding
Nucleotide Protein
Heading Accession and Version

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