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Rgs12 regulator of G protein signaling 12 [ Marmota marmota marmota (Alpine marmot) ]

Gene ID: 107139099, updated on 1-Aug-2024

Summary

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Gene symbol
Rgs12
Gene description
regulator of G protein signaling 12
See related
Ensembl:ENSMMMG00000012736
Gene type
protein coding
RefSeq status
MODEL
Organism
Marmota marmota marmota (sub-species: marmota)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciuromorpha; Sciuridae; Xerinae; Marmotini; Marmota
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
101 current marMar (GCF_001458135.2) Unplaced Scaffold NW_026000108.1 (2536115..2651739)
100 previous assembly marMar2.1 (GCF_001458135.1) Unplaced Scaffold NW_015351219.1 (2556032..2651739)

NW_026000108.1Genomic Context describing neighboring genes Neighboring gene huntingtin Neighboring gene Myb/SANT DNA binding domain containing 1 Neighboring gene uncharacterized LOC125610907 Neighboring gene HGF activator Neighboring gene docking protein 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
regulator of G-protein signaling 12

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Marmota marmota marmota Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference marMar

Genomic

  1. NW_026000108.1 Reference marMar

    Range
    2536115..2651739
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015481904.2 → XP_015337390.1  regulator of G-protein signaling 12 isoform X1

    UniProtKB/TrEMBL
    A0A8C5ZJ92, A0AAJ7AEQ3
    Related
    ENSMMMP00000014599.1
    Conserved Domains (9) summary
    smart00455
    Location:1027 → 1096
    RBD; Raf-like Ras-binding domain
    cd01817
    Location:955 → 1027
    RGS12_RBD; Ubiquitin domain of RGS12 and RGS14
    cd08742
    Location:708 → 822
    RGS_RGS12; Regulator of G protein signaling (RGS) domain found in the RGS12 protein
    cd00992
    Location:11 → 86
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    cd13162
    Location:219 → 350
    PTB_RGS12; Regulator of G-protein signaling 12 Phosphotyrosine-binding (PTB) PH-like fold
    pfam02188
    Location:1180 → 1201
    GoLoco; GoLoco motif
    pfam16611
    Location:1098 → 1168
    RGS12_us2; Unstructured region between RBD and GoLoco
    pfam16612
    Location:1245 → 1363
    RGS12_usC; C-terminal unstructured region of RGS12
    pfam16613
    Location:828 → 925
    RGS12_us1; Unstructured region of RGS12

  2. XM_048784082.1 → XP_048640039.1  regulator of G-protein signaling 12 isoform X2

    UniProtKB/TrEMBL
    A0A8C5ZJ92, A0AAJ8CNS0

  3. XM_048784083.1 → XP_048640040.1  regulator of G-protein signaling 12 isoform X3

    UniProtKB/TrEMBL
    A0AAJ8CNV6

  4. XM_048784084.1 → XP_048640041.1  regulator of G-protein signaling 12 isoform X4

    UniProtKB/TrEMBL
    A0A8C6ETW6, A0AAJ8CNR7
Nucleotide Protein
Heading Accession and Version

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