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BACE2 beta-secretase 2 [ Acinonyx jubatus (cheetah) ]

Gene ID: 106965624, updated on 13-Mar-2024

Summary

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Gene symbol
BACE2
Gene description
beta-secretase 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Acinonyx jubatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Acinonychinae; Acinonyx
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: C2
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_04 current VMU_Ajub_asm_v1.0 (GCF_027475565.1) C2 NC_069384.1 (4583005..4673001, complement)

Chromosome C2 - NC_069384.1Genomic Context describing neighboring genes Neighboring gene FAM3 metabolism regulating signaling molecule B Neighboring gene uncharacterized LOC128315100 Neighboring gene uncharacterized LOC128315099 Neighboring gene uncharacterized LOC128315101 Neighboring gene uncharacterized LOC113594457 Neighboring gene uncharacterized LOC113594424

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_069384.1 Chromosome C2 Reference VMU_Ajub_asm_v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables aspartic-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in amyloid-beta metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in trans-Golgi network IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
beta-secretase 2
Names
beta-site APP-cleaving enzyme 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_027475565.1-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference VMU_Ajub_asm_v1.0

Genomic

  1. NC_069384.1 Reference VMU_Ajub_asm_v1.0

    Range
    4583005..4673001 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_053220538.1 → XP_053076513.1  beta-secretase 2 isoform X1

  2. XM_053220539.1 → XP_053076514.1  beta-secretase 2 isoform X2

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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