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LRP2 LDL receptor related protein 2 [ Calidris pugnax (ruff) ]

Gene ID: 106895326, updated on 3-Aug-2024

Summary

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Gene symbol
LRP2
Gene description
LDL receptor related protein 2
See related
Ensembl:ENSCPUG00000003962
Gene type
protein coding
RefSeq status
MODEL
Organism
Calidris pugnax
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Charadriiformes; Scolopacidae; Calidris
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
79
Annotation release Status Assembly Chr Location
100 current ASM143184v1 (GCF_001431845.1) Unplaced Scaffold NW_015090990.1 (7339059..7463420, complement)

NW_015090990.1Genomic Context describing neighboring genes Neighboring gene ATP binding cassette subfamily B member 11 Neighboring gene dehydrogenase/reductase 9 Neighboring gene retinol dehydrogenase 7-like Neighboring gene collagen alpha-1(XXVIII) chain-like Neighboring gene Bardet-Biedl syndrome 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015090990.1 Unplaced Scaffold Reference ASM143184v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
low-density lipoprotein receptor-related protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Calidris pugnax Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM143184v1

Genomic

  1. NW_015090990.1 Reference ASM143184v1

    Range
    7339059..7463420 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014954693.1 → XP_014810179.1  low-density lipoprotein receptor-related protein 2 isoform X2

    Related
    ENSCPUP00000005943.1, ENSCPUT00000007217.1
    Conserved Domains (11) summary
    smart00192
    Location:2907 → 2939
    LDLa; Low-density lipoprotein receptor domain class A
    smart00135
    Location:3360 → 3401
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00179
    Location:1392 → 1431
    EGF_CA; Calcium-binding EGF-like domain
    COG3391
    Location:1730 → 2030
    YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
    cd00112
    Location:3721 → 3756
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd05819
    Location:2108 → 2144
    NHL; NHL repeat [structural motif]
    pfam00057
    Location:71 → 104
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam00058
    Location:2521 → 2561
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    pfam14670
    Location:1355 → 1390
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:3149 → 3192
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl18310
    Location:2107 → 2302
    NHL; NHL repeat unit of beta-propeller proteins

  2. XM_014954694.1 → XP_014810180.1  low-density lipoprotein receptor-related protein 2 isoform X3

    Related
    ENSCPUP00000005726.1, ENSCPUT00000006953.1
    Conserved Domains (11) summary
    smart00192
    Location:2907 → 2939
    LDLa; Low-density lipoprotein receptor domain class A
    smart00135
    Location:3360 → 3401
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00179
    Location:1392 → 1431
    EGF_CA; Calcium-binding EGF-like domain
    COG3391
    Location:1730 → 2030
    YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
    cd00112
    Location:3721 → 3756
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd05819
    Location:2108 → 2144
    NHL; NHL repeat [structural motif]
    pfam00057
    Location:71 → 104
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam00058
    Location:2521 → 2561
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    pfam14670
    Location:1355 → 1390
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:3149 → 3192
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl18310
    Location:2107 → 2302
    NHL; NHL repeat unit of beta-propeller proteins

  3. XM_014954692.1 → XP_014810178.1  low-density lipoprotein receptor-related protein 2 isoform X1

    Related
    ENSCPUP00000005917.1, ENSCPUT00000007191.1
    Conserved Domains (11) summary
    smart00192
    Location:2907 → 2939
    LDLa; Low-density lipoprotein receptor domain class A
    smart00135
    Location:3360 → 3401
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00179
    Location:1392 → 1431
    EGF_CA; Calcium-binding EGF-like domain
    COG3391
    Location:1730 → 2030
    YncE; DNA-binding beta-propeller fold protein YncE [General function prediction only]
    cd00112
    Location:3721 → 3756
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd05819
    Location:2108 → 2144
    NHL; NHL repeat [structural motif]
    pfam00057
    Location:71 → 104
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam00058
    Location:2521 → 2561
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    pfam14670
    Location:1355 → 1390
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:3149 → 3192
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl18310
    Location:2107 → 2302
    NHL; NHL repeat unit of beta-propeller proteins
Nucleotide Protein
Heading Accession and Version

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