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SMURF2 SMAD specific E3 ubiquitin protein ligase 2 [ Calidris pugnax (ruff) ]

Gene ID: 106893907, updated on 3-Aug-2024

Summary

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Gene symbol
SMURF2
Gene description
SMAD specific E3 ubiquitin protein ligase 2
See related
Ensembl:ENSCPUG00000019035
Gene type
protein coding
RefSeq status
MODEL
Organism
Calidris pugnax
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Charadriiformes; Scolopacidae; Calidris
Orthologs
human mouse all
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Genomic context

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See SMURF2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
19
Annotation release Status Assembly Chr Location
100 current ASM143184v1 (GCF_001431845.1) Unplaced Scaffold NW_015090957.1 (2495876..2561750)

NW_015090957.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106893911 Neighboring gene karyopherin subunit alpha 2 Neighboring gene centrosomal protein 95 Neighboring gene DEAD-box helicase 5 Neighboring gene DNA polymerase gamma 2, accessory subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015090957.1 Unplaced Scaffold Reference ASM143184v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of BMP signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase SMURF2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Calidris pugnax Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM143184v1

Genomic

  1. NW_015090957.1 Reference ASM143184v1

    Range
    2495876..2561750
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014952228.1 → XP_014807714.1  E3 ubiquitin-protein ligase SMURF2

    Related
    ENSCPUP00000028280.1, ENSCPUT00000033291.1
    Conserved Domains (5) summary
    cd08382
    Location:13 → 137
    C2_Smurf-like; C2 domain present in Smad ubiquitination-related factor (Smurf)-like proteins
    smart00456
    Location:298 → 330
    WW; Domain with 2 conserved Trp (W) residues
    smart00119
    Location:423 → 748
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd00078
    Location:396 → 748
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    pfam00397
    Location:159 → 188
    WW; WW domain
Nucleotide Protein
Heading Accession and Version

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