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PCK1 phosphoenolpyruvate carboxykinase 1 [ Equus asinus (ass) ]

Gene ID: 106825233, updated on 13-Mar-2024

Summary

Gene symbol
PCK1
Gene description
phosphoenolpyruvate carboxykinase 1
See related
Ensembl:ENSEASG00005023259
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus asinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
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Genomic context

Location:
chromosome: 15
Exon count:
10
Annotation release Status Assembly Chr Location
101 current ASM1607732v2 (GCF_016077325.2) 15 NC_052191.1 (44356221..44361636)
100 previous assembly ASM130575v1 (GCF_001305755.1) Unplaced Scaffold NW_014636980.1 (3305695..3310684, complement)

Chromosome 15 - NC_052191.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106825251 Neighboring gene CCCTC-binding factor like Neighboring gene uncharacterized LOC123277228 Neighboring gene Z-DNA binding protein 1

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables manganese ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables phosphoenolpyruvate carboxykinase (GTP) activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cellular response to dexamethasone stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to glucose stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in gluconeogenesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in glycerol biosynthetic process from pyruvate IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in hepatocyte differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in propionate catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to starvation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
phosphoenolpyruvate carboxykinase, cytosolic [GTP]

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus asinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1607732v2

Genomic

  1. NC_052191.1 Reference ASM1607732v2

    Range
    44356221..44361636
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014831923.2XP_014687409.2  phosphoenolpyruvate carboxykinase, cytosolic [GTP]

    UniProtKB/TrEMBL
    A0A8C4MY11
    Related
    ENSEASP00005034021.1, ENSEAST00005037089.2
    Conserved Domains (1) summary
    cd00819
    Location:27615
    PEPCK_GTP; Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and ...