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MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like [ Thamnophis sirtalis ]

Gene ID: 106552377, updated on 13-Mar-2024

Summary

Gene symbol
MTHFD1L
Gene description
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like
Gene type
protein coding
RefSeq status
MODEL
Organism
Thamnophis sirtalis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Colubridae; Natricinae; Thamnophis
Annotation information
Annotation category: partial on reference assembly
Orthologs
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Genomic context

Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
100 current Thamnophis_sirtalis-6.0 (GCF_001077635.1) Unplaced Scaffold NW_013659635.1 (119546..203138, complement)

NW_013659635.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106552378

Genomic regions, transcripts, and products

Genomic Sequence:
NW_013659635.1 Unplaced Scaffold Reference Thamnophis_sirtalis-6.0

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables formate-tetrahydrofolate ligase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
monofunctional C1-tetrahydrofolate synthase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Thamnophis sirtalis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Thamnophis_sirtalis-6.0

Genomic

  1. NW_013659635.1 Reference Thamnophis_sirtalis-6.0

    Range
    119546..203138 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_014070632.1XP_013926107.1  monofunctional C1-tetrahydrofolate synthase, mitochondrial

    UniProtKB/TrEMBL
    A0A6I9YP92
    Conserved Domains (4) summary
    PLN02759
    Location:279904
    PLN02759; Formate--tetrahydrofolate ligase
    COG0190
    Location:15137
    FolD; 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme transport and metabolism]
    pfam00763
    Location:1103
    THF_DHG_CYH; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
    cl21454
    Location:117260
    NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins