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Hck HCK proto-oncogene, Src family tyrosine kinase [ Dipodomys ordii (Ord's kangaroo rat) ]

Gene ID: 105981479, updated on 11-Apr-2024

Summary

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Gene symbol
Hck
Gene description
HCK proto-oncogene, Src family tyrosine kinase
See related
Ensembl:ENSDORG00000005152
Gene type
protein coding
RefSeq status
MODEL
Organism
Dipodomys ordii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Heteromyidae; Dipodomyinae; Dipodomys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
100 current Dord_2.0 (GCF_000151885.1) Unplaced Scaffold NW_012267229.1 (13447377..13482973)

NW_012267229.1Genomic Context describing neighboring genes Neighboring gene p53 and DNA damage regulated 1 Neighboring gene XK related 7 Neighboring gene CCM2 like scaffold protein Neighboring gene transmembrane 9 superfamily member 4 Neighboring gene putative testis-specific Y-encoded-like protein 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012267229.1 Unplaced Scaffold Reference Dord_2.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase HCK

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Dipodomys ordii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Dord_2.0

Genomic

  1. NW_012267229.1 Reference Dord_2.0

    Range
    13447377..13482973
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_013010670.1 → XP_012866124.1  tyrosine-protein kinase HCK

    UniProtKB/TrEMBL
    A0A1S3EQC8
    Related
    ENSDORP00000024762.1, ENSDORT00000030974.1
    Conserved Domains (4) summary
    cd10363
    Location:96 → 195
    SH2_Src_HCK; Src homology 2 (SH2) domain found in HCK
    pfam07714
    Location:216 → 465
    Pkinase_Tyr; Protein tyrosine kinase
    cl17036
    Location:69 → 100
    SH3; Src Homology 3 domain superfamily
    cl21453
    Location:208 → 478
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
Heading Accession and Version

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