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ror1 receptor tyrosine kinase-like orphan receptor 1 [ Fundulus heteroclitus (mummichog) ]

Gene ID: 105936984, updated on 20-Aug-2024

Summary

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Gene symbol
ror1
Gene description
receptor tyrosine kinase-like orphan receptor 1
See related
EnsemblRapid:ENSFHEG00000001360
Gene type
protein coding
RefSeq status
MODEL
Organism
Fundulus heteroclitus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Fundulidae; Fundulus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 9
Exon count:
11
Annotation release Status Assembly Chr Location
102 current MU-UCD_Fhet_4.1 (GCF_011125445.2) 9 NC_046369.1 (6174081..6238661)
101 previous assembly Fundulus_heteroclitus-3.0.2 (GCF_000826765.1) Unplaced Scaffold NW_012234465.1 (3721418..3890067)

Chromosome 9 - NC_046369.1Genomic Context describing neighboring genes Neighboring gene EF-hand calcium binding domain 7 Neighboring gene phosphoglucomutase 1 Neighboring gene uncharacterized LOC110369492 Neighboring gene cache domain containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in multicellular organism development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
inactive tyrosine-protein kinase transmembrane receptor ROR1
Names
Receptor tyrosine kinase orphan receptor 1
Tyrosine-protein kinase transmembrane receptor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Fundulus heteroclitus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MU-UCD_Fhet_4.1 Primary Assembly

Genomic

  1. NC_046369.1 Reference MU-UCD_Fhet_4.1 Primary Assembly

    Range
    6174081..6238661
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036140903.1 → XP_035996796.1  inactive tyrosine-protein kinase transmembrane receptor ROR1

    UniProtKB/TrEMBL
    A0A3Q2NNY7
    Related
    ENSFHEP00000000630.2, ENSFHET00000015193.2
    Conserved Domains (5) summary
    cd00108
    Location:288 → 370
    KR; Kringle domain; Kringle domains are believed to play a role in binding mediators, such as peptides, other proteins, membranes, or phospholipids. They are autonomous structural domains, found in a varying number of copies, in blood clotting and ...
    cd05090
    Location:445 → 727
    PTKc_Ror1; Catalytic domain of the Protein Tyrosine Kinase, Receptor tyrosine kinase-like Orphan Receptor 1
    pfam07679
    Location:40 → 125
    I-set; Immunoglobulin I-set domain
    cd00096
    Location:43 → 46
    Ig; Ig strand A' [structural motif]
    cl02447
    Location:144 → 285
    CRD_FZ; CRD_domain cysteine-rich domain, also known as Fz (frizzled) domain
Nucleotide Protein
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