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top2a DNA topoisomerase II alpha [ Clupea harengus (Atlantic herring) ]

Gene ID: 105909126, updated on 18-Jun-2024

Summary

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Gene symbol
top2a
Gene description
DNA topoisomerase II alpha
See related
Ensembl:ENSCHAG00020004796
Gene type
protein coding
RefSeq status
MODEL
Organism
Clupea harengus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Clupei; Clupeiformes; Clupeoidei; Clupeidae; Clupea
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 1
Exon count:
35
Annotation release Status Assembly Chr Location
102 current Ch_v2.0.2 (GCF_900700415.2) 1 NC_045152.1 (12772067..12797172)

Chromosome 1 - NC_045152.1Genomic Context describing neighboring genes Neighboring gene mediator complex subunit 24 Neighboring gene leucine rich repeat containing 3Ca Neighboring gene gap junction delta-3 protein-like Neighboring gene gap junction delta-3 protein-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_045152.1 Chromosome 1 Reference Ch_v2.0.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA topological change IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in resolution of meiotic recombination intermediates IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sister chromatid segregation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA topoisomerase 2-alpha
Names
topoisomerase (DNA) II alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Clupea harengus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Ch_v2.0.2 Primary Assembly

Genomic

  1. NC_045152.1 Reference Ch_v2.0.2 Primary Assembly

    Range
    12772067..12797172
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_031567903.2 → XP_031423763.1  DNA topoisomerase 2-alpha isoform X1

    UniProtKB/TrEMBL
    A0A6P8F5H9
    Related
    ENSCHAP00020010358.1, ENSCHAT00020011192.1
    Conserved Domains (1) summary
    PTZ00108
    Location:25 → 1416
    PTZ00108; DNA topoisomerase 2-like protein; Provisional

  2. XM_031567911.2 → XP_031423771.1  DNA topoisomerase 2-alpha isoform X2

    UniProtKB/TrEMBL
    A0A6P8FE21
    Conserved Domains (1) summary
    PTZ00108
    Location:25 → 1433
    PTZ00108; DNA topoisomerase 2-like protein; Provisional

  3. XM_031567919.2 → XP_031423779.1  DNA topoisomerase 2-alpha isoform X3

    UniProtKB/TrEMBL
    A0A6P8FE21
    Conserved Domains (1) summary
    PTZ00108
    Location:25 → 1433
    PTZ00108; DNA topoisomerase 2-like protein; Provisional
Nucleotide Protein
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