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RASA3 RAS p21 protein activator 3 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105871894, updated on 13-Mar-2024

Summary

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Gene symbol
RASA3
Gene description
RAS p21 protein activator 3
See related
Ensembl:ENSMICG00000006158
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 13
Exon count:
26
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 13 NC_033672.1 (86677957..86758390, complement)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012195920.1 (162503..247340)

Chromosome 13 - NC_033672.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105871941 Neighboring gene chromosome 13 C13orf46 homolog Neighboring gene non-histone chromosomal protein HMG-14 pseudogene Neighboring gene uncharacterized protein C17orf105 homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras GTPase-activating protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033672.1 Reference Mmur_3.0 Primary Assembly

    Range
    86677957..86758390 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012765528.2 → XP_012620982.2  ras GTPase-activating protein 3 isoform X3

    UniProtKB/TrEMBL
    A0A8B7GE66
    Related
    ENSMICP00000005618.3, ENSMICT00000006165.3
    Conserved Domains (5) summary
    smart00107
    Location:679 → 714
    BTK; Bruton's tyrosine kinase Cys-rich motif
    cd04010
    Location:146 → 288
    C2B_RasA3; C2 domain second repeat present in RAS p21 protein activator 3 (RasA3)
    cd08401
    Location:13 → 133
    C2A_RasA2_RasA3; C2 domain first repeat present in RasA2 and RasA3
    cd05134
    Location:297 → 565
    RasGAP_RASA3; Ras-GTPase Activating Domain of RASA3
    cd13371
    Location:562 → 686
    PH_GAP1_mammal-like; GAP1(IP4BP) pleckstrin homology (PH) domain

  2. XM_020290530.1 → XP_020146119.1  ras GTPase-activating protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A8B7XFJ3
    Conserved Domains (5) summary
    smart00107
    Location:705 → 740
    BTK; Bruton's tyrosine kinase Cys-rich motif
    cd04010
    Location:146 → 314
    C2B_RasA3; C2 domain second repeat present in RAS p21 protein activator 3 (RasA3)
    cd08401
    Location:13 → 133
    C2A_RasA2_RasA3; C2 domain first repeat present in RasA2 and RasA3
    cd05134
    Location:323 → 591
    RasGAP_RASA3; Ras-GTPase Activating Domain of RASA3
    cd13371
    Location:588 → 712
    PH_GAP1_mammal-like; GAP1(IP4BP) pleckstrin homology (PH) domain

  3. XM_020290531.1 → XP_020146120.1  ras GTPase-activating protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A8B7XFY5
    Conserved Domains (3) summary
    smart00107
    Location:296 → 331
    BTK; Bruton's tyrosine kinase Cys-rich motif
    cd13371
    Location:179 → 303
    PH_GAP1_mammal-like; GAP1(IP4BP) pleckstrin homology (PH) domain
    cl02569
    Location:1 → 182
    RasGAP; Ras GTPase Activating Domain

  4. XM_020290529.1 → XP_020146118.1  ras GTPase-activating protein 3 isoform X1

    UniProtKB/TrEMBL
    A0A8B7XFY5
    Conserved Domains (3) summary
    smart00107
    Location:296 → 331
    BTK; Bruton's tyrosine kinase Cys-rich motif
    cd13371
    Location:179 → 303
    PH_GAP1_mammal-like; GAP1(IP4BP) pleckstrin homology (PH) domain
    cl02569
    Location:1 → 182
    RasGAP; Ras GTPase Activating Domain
Nucleotide Protein
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