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CELSR1 cadherin EGF LAG seven-pass G-type receptor 1 [ Microcebus murinus (gray mouse lemur) ]

Gene ID: 105867160, updated on 13-Mar-2024

Summary

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Gene symbol
CELSR1
Gene description
cadherin EGF LAG seven-pass G-type receptor 1
See related
Ensembl:ENSMICG00000005998
Gene type
protein coding
RefSeq status
MODEL
Organism
Microcebus murinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Cheirogaleidae; Microcebus
Orthologs
human mouse all
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Genomic context

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See CELSR1 in Genome Data Viewer
Location:
chromosome: 7
Exon count:
35
Annotation release Status Assembly Chr Location
101 current Mmur_3.0 (GCF_000165445.2) 7 NC_033666.1 (9505684..9660191, complement)
100 previous assembly Mmur_2.0 (GCF_000165445.1) Unplaced Scaffold NW_012195576.1 (885538..1040050)

Chromosome 7 - NC_033666.1Genomic Context describing neighboring genes Neighboring gene G2 and S-phase expressed 1 Neighboring gene tRNA mitochondrial 2-thiouridylase Neighboring gene uncharacterized LOC105867205 Neighboring gene GRAM domain containing 4 Neighboring gene ceramide kinase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cadherin EGF LAG seven-pass G-type receptor 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Microcebus murinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mmur_3.0 Primary Assembly

Genomic

  1. NC_033666.1 Reference Mmur_3.0 Primary Assembly

    Range
    9505684..9660191 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012756960.1 → XP_012612414.1  cadherin EGF LAG seven-pass G-type receptor 1 isoform X2

    UniProtKB/TrEMBL
    A0A8B7FTI8, A0A8C5UVS1
    Related
    ENSMICP00000005493.3, ENSMICT00000006022.3
    Conserved Domains (8) summary
    smart00303
    Location:2431 → 2484
    GPS; G-protein-coupled receptor proteolytic site domain
    cd11304
    Location:816 → 911
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00008
    Location:2075 → 2128
    HormR; Domain present in hormone receptors
    cd00054
    Location:1387 → 1422
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:2025 → 2063
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:1467 → 1650
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam16489
    Location:2154 → 2403
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl21561
    Location:2518 → 2721
    7tm_4; Olfactory receptor

  2. XM_012756954.1 → XP_012612408.1  cadherin EGF LAG seven-pass G-type receptor 1 isoform X1

    UniProtKB/TrEMBL
    A0A8B7FTI4, A0A8C5UVS1
    Conserved Domains (8) summary
    smart00303
    Location:2431 → 2484
    GPS; G-protein-coupled receptor proteolytic site domain
    cd11304
    Location:816 → 911
    Cadherin_repeat; Cadherin tandem repeat domain
    smart00008
    Location:2075 → 2128
    HormR; Domain present in hormone receptors
    cd00054
    Location:1387 → 1422
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:2025 → 2063
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:1467 → 1650
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    pfam16489
    Location:2154 → 2403
    GAIN; GPCR-Autoproteolysis INducing (GAIN) domain
    cl21561
    Location:2518 → 2721
    7tm_4; Olfactory receptor
Nucleotide Protein
Heading Accession and Version

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