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GART phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase [ Propithecus coquereli (Coquerel's sifaka) ]

Gene ID: 105820825, updated on 13-Mar-2024

Summary

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Gene symbol
GART
Gene description
phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
See related
Ensembl:ENSPCOG00000015014
Gene type
protein coding
RefSeq status
MODEL
Organism
Propithecus coquereli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Indriidae; Propithecus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
100 current Pcoq_1.0 (GCF_000956105.1) Unplaced Scaffold NW_012151285.1 (1090174..1116664)

NW_012151285.1Genomic Context describing neighboring genes Neighboring gene DNA replication fork stabilization factor DONSON Neighboring gene SON DNA and RNA binding protein Neighboring gene DnaJ heat shock protein family (Hsp40) member C28 Neighboring gene transmembrane protein 50B

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012151285.1 Unplaced Scaffold Reference Pcoq_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphoribosylamine-glycine ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphoribosylformylglycinamidine cyclo-ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphoribosylglycinamide formyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in 'de novo' IMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in adenine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
trifunctional purine biosynthetic protein adenosine-3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Propithecus coquereli Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pcoq_1.0 Primary Assembly

Genomic

  1. NW_012151285.1 Reference Pcoq_1.0 Primary Assembly

    Range
    1090174..1116664
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012657389.1 → XP_012512843.1  trifunctional purine biosynthetic protein adenosine-3

    UniProtKB/TrEMBL
    A0A2K6F0M4
    Related
    ENSPCOP00000007541.1, ENSPCOT00000018085.1
    Conserved Domains (7) summary
    cd02196
    Location:469 → 767
    PurM; PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis. ...
    cd08645
    Location:809 → 991
    FMT_core_GART; Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART)
    PRK00885
    Location:4 → 427
    PRK00885; phosphoribosylamine--glycine ligase; Provisional
    PRK05385
    Location:435 → 766
    PRK05385; phosphoribosylaminoimidazole synthetase; Provisional
    pfam01071
    Location:105 → 298
    GARS_A; Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain
    pfam02843
    Location:334 → 424
    GARS_C; Phosphoribosylglycinamide synthetase, C domain
    pfam02844
    Location:4 → 104
    GARS_N; Phosphoribosylglycinamide synthetase, N domain
Nucleotide Protein
Heading Accession and Version

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