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TIMP3 TIMP metallopeptidase inhibitor 3 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105575771, updated on 19-Jun-2024

Summary

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Gene symbol
TIMP3
Gene description
TIMP metallopeptidase inhibitor 3
See related
Ensembl:ENSCATG00000042645
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
5
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012004276.1 (8205558..8268557)

NW_012004276.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105575773 Neighboring gene uncharacterized LOC105575772 Neighboring gene synapsin III Neighboring gene LARGE xylosyl- and glucuronyltransferase 1 Neighboring gene aconitate hydratase, mitochondrial pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012004276.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metalloendopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protease binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of membrane protein ectodomain proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular matrix IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
metalloproteinase inhibitor 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012004276.1 Reference Caty_1.0

    Range
    8205558..8268557
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012038003.1 → XP_011893393.1  metalloproteinase inhibitor 3

    See identical proteins and their annotated locations for XP_011893393.1

    UniProtKB/TrEMBL
    A0A2K5NRJ2
    Related
    ENSCATP00000040148.1, ENSCATT00000064465.1
    Conserved Domains (1) summary
    cd03585
    Location:24 → 200
    NTR_TIMP; NTR domain, TIMP subfamily; TIMPs, or tissue inibitors of metalloproteases, are essential regulators of extracellular matrix turnover and remodeling. They form complexes with matrix metalloproteases (MMPs) and inactivate them irreversibly by ...
Nucleotide Protein
Heading Accession and Version

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