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TFPI tissue factor pathway inhibitor [ Mandrillus leucophaeus (drill) ]

Gene ID: 105553898, updated on 13-Mar-2024

Summary

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Gene symbol
TFPI
Gene description
tissue factor pathway inhibitor
See related
Ensembl:ENSMLEG00000038295
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012106642.1 (1183364..1281833, complement)

NW_012106642.1Genomic Context describing neighboring genes Neighboring gene inosine-5'-monophosphate dehydrogenase 1 pseudogene Neighboring gene calcitonin receptor like receptor Neighboring gene hsc70-interacting protein pseudogene Neighboring gene uncharacterized protein C18orf25 pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012106642.1 Unplaced Scaffold Reference Mleu.le_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of peptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tissue factor pathway inhibitor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012106642.1 Reference Mleu.le_1.0

    Range
    1183364..1281833 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012000078.1 → XP_011855468.1  tissue factor pathway inhibitor isoform X1

    See identical proteins and their annotated locations for XP_011855468.1

    UniProtKB/TrEMBL
    A0A2K5ZK23
    Conserved Domains (2) summary
    cd00109
    Location:123 → 175
    KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
    pfam00014
    Location:216 → 268
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain

  2. XM_012000079.1 → XP_011855469.1  tissue factor pathway inhibitor isoform X1

    See identical proteins and their annotated locations for XP_011855469.1

    UniProtKB/TrEMBL
    A0A2K5ZK23
    Related
    ENSMLEP00000028167.1, ENSMLET00000051719.1
    Conserved Domains (2) summary
    cd00109
    Location:123 → 175
    KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
    pfam00014
    Location:216 → 268
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain

  3. XM_012000080.1 → XP_011855470.1  tissue factor pathway inhibitor isoform X2

    See identical proteins and their annotated locations for XP_011855470.1

    UniProtKB/TrEMBL
    A0A2K5ZK19
    Related
    ENSMLEP00000028171.1, ENSMLET00000051723.1
    Conserved Domains (2) summary
    cd00109
    Location:123 → 175
    KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
    pfam00014
    Location:53 → 104
    Kunitz_BPTI; Kunitz/Bovine pancreatic trypsin inhibitor domain
Nucleotide Protein
Heading Accession and Version

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