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IQGAP2 IQ motif containing GTPase activating protein 2 [ Mandrillus leucophaeus (drill) ]

Gene ID: 105551223, updated on 13-Mar-2024

Summary

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Gene symbol
IQGAP2
Gene description
IQ motif containing GTPase activating protein 2
See related
Ensembl:ENSMLEG00000027862
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
38
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012099654.1 (1833448..2164795, complement)

NW_012099654.1Genomic Context describing neighboring genes Neighboring gene F2R like trypsin receptor 1 Neighboring gene coagulation factor II thrombin receptor Neighboring gene uncharacterized LOC105551196 Neighboring gene coagulation factor II thrombin receptor like 2 Neighboring gene U1 small nuclear ribonucleoprotein C pseudogene Neighboring gene synaptic vesicle glycoprotein 2C

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012099654.1 Unplaced Scaffold Reference Mleu.le_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras GTPase-activating-like protein IQGAP2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012099654.1 Reference Mleu.le_1.0

    Range
    1833448..2164795 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011996387.1 → XP_011851777.1  ras GTPase-activating-like protein IQGAP2 isoform X1

    UniProtKB/TrEMBL
    A0A2K5XWY8
    Related
    ENSMLEP00000007824.1, ENSMLET00000031177.1
    Conserved Domains (4) summary
    smart00323
    Location:878 → 1207
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd00014
    Location:15 → 129
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam03836
    Location:1340 → 1471
    RasGAP_C; RasGAP C-terminus
    cl02569
    Location:889 → 1247
    RasGAP; Ras GTPase Activating Domain

  2. XM_011996395.1 → XP_011851785.1  ras GTPase-activating-like protein IQGAP2 isoform X2

    UniProtKB/TrEMBL
    A0A2K5XWX4, A0A2K5XX23
    Related
    ENSMLEP00000007809.1, ENSMLET00000031162.1
    Conserved Domains (4) summary
    smart00323
    Location:855 → 1184
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd00014
    Location:1 → 106
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    pfam03836
    Location:1317 → 1448
    RasGAP_C; RasGAP C-terminus
    cl02569
    Location:866 → 1224
    RasGAP; Ras GTPase Activating Domain

  3. XM_011996408.1 → XP_011851798.1  ras GTPase-activating-like protein IQGAP2 isoform X4

    Conserved Domains (2) summary
    cl02569
    Location:412 → 770
    RasGAP; Ras GTPase Activating Domain
    cl27227
    Location:280 → 1071
    RasGAP_C; RasGAP C-terminus

  4. XM_011996402.1 → XP_011851792.1  ras GTPase-activating-like protein IQGAP2 isoform X3

    UniProtKB/TrEMBL
    A0A2K5XWY0
    Related
    ENSMLEP00000007814.1, ENSMLET00000031167.1
    Conserved Domains (2) summary
    cl02569
    Location:412 → 770
    RasGAP; Ras GTPase Activating Domain
    cl27227
    Location:280 → 1071
    RasGAP_C; RasGAP C-terminus
Nucleotide Protein
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