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C1S complement C1s [ Camelus dromedarius (Arabian camel) ]

Gene ID: 105098188, updated on 19-Apr-2024

Summary

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Gene symbol
C1S
Gene description
complement C1s
Locus tag
Cadr_000029349
Gene type
protein coding
RefSeq status
MODEL
Organism
Camelus dromedarius
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 25
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_04 current mCamDro1.pat (GCF_036321535.1) 25 NC_087460.1 (5129783..5138964)
101 previous assembly CamDro3 (GCF_000803125.2) 34 NC_044544.1 (17222850..17232028, complement)

Chromosome 25 - NC_087460.1Genomic Context describing neighboring genes Neighboring gene EMG1 N1-specific pseudouridine methyltransferase Neighboring gene lysophosphatidylcholine acyltransferase 3 Neighboring gene complement C1r Neighboring gene complement C1r subcomponent like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
complement C1s subcomponent
Names
Complement C1s subcomponent

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036321535.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCamDro1.pat

Genomic

  1. NC_087460.1 Reference mCamDro1.pat

    Range
    5129783..5138964
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010990821.3 → XP_010989123.2  complement C1s subcomponent

    UniProtKB/TrEMBL
    A0A5N4C601
    Conserved Domains (5) summary
    cd00033
    Location:300 → 361
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd00041
    Location:24 → 135
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:444 → 685
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00431
    Location:181 → 293
    CUB; CUB domain
    pfam14670
    Location:149 → 177
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
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