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SRGAP3 SLIT-ROBO Rho GTPase activating protein 3 [ Camelus dromedarius (Arabian camel) ]

Gene ID: 105093145, updated on 19-Apr-2024

Summary

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Gene symbol
SRGAP3
Gene description
SLIT-ROBO Rho GTPase activating protein 3
Locus tag
Cadr_000020641
Gene type
protein coding
RefSeq status
MODEL
Organism
Camelus dromedarius
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 17
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2024_04 current mCamDro1.pat (GCF_036321535.1) 17 NC_087452.1 (6441410..6662048)
101 previous assembly CamDro3 (GCF_000803125.2) 17 NC_044527.1 (45216251..45503807, complement)

Chromosome 17 - NC_087452.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC135323333 Neighboring gene THUMP domain containing 3 Neighboring gene uncharacterized LOC116158290 Neighboring gene RAD18 E3 ubiquitin protein ligase Neighboring gene oxytocin receptor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
SLIT-ROBO Rho GTPase-activating protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_036321535.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mCamDro1.pat

Genomic

  1. NC_087452.1 Reference mCamDro1.pat

    Range
    6441410..6662048
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_064496289.1 → XP_064352359.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X1

  2. XM_031470812.2 → XP_031326672.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X2

    Conserved Domains (3) summary
    cd07684
    Location:26 → 278
    F-BAR_srGAP3; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 3
    cd11955
    Location:748 → 800
    SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
    cd04383
    Location:502 → 689
    RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...

  3. XM_031470813.2 → XP_031326673.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X3

    Conserved Domains (3) summary
    cd07684
    Location:26 → 278
    F-BAR_srGAP3; The F-BAR (FES-CIP4 Homology and Bin/Amphiphysin/Rvs) domain of Slit-Robo GTPase Activating Protein 3
    cd11955
    Location:724 → 776
    SH3_srGAP1-3; Src homology 3 domain of Slit-Robo GTPase Activating Proteins 1, 2, and 3
    cd04383
    Location:481 → 665
    RhoGAP_srGAP; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain present in srGAPs. srGAPs are components of the intracellular part of Slit-Robo signalling pathway that is important for axon guidance and cell migration. srGAPs contain an ...

  4. XM_064496290.1 → XP_064352360.1  SLIT-ROBO Rho GTPase-activating protein 3 isoform X4

RNA

  1. XR_010384781.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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