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PKM pyruvate kinase M1/2 [ Bison bison bison ]

Gene ID: 104982069, updated on 12-Mar-2024

Summary

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Gene symbol
PKM
Gene description
pyruvate kinase M1/2
See related
Ensembl:ENSBBBG00000000597
Gene type
protein coding
RefSeq status
MODEL
Organism
Bison bison bison (sub-species: bison)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bison
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
100 current Bison_UMD1.0 (GCF_000754665.1) Unplaced Scaffold NW_011495077.1 (4447747..4474286)

NW_011495077.1Genomic Context describing neighboring genes Neighboring gene CUGBP Elav-like family member 6 Neighboring gene poly(ADP-ribose) polymerase family member 6 Neighboring gene T-cell receptor alpha chain V region 2B4-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011495077.1 Unplaced Scaffold Reference Bison_UMD1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables magnesium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables pyruvate kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to insulin stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycolytic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pyruvate kinase PKM
Names
pyruvate kinase, muscle

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bison bison bison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bison_UMD1.0 Primary Assembly

Genomic

  1. NW_011495077.1 Reference Bison_UMD1.0 Primary Assembly

    Range
    4447747..4474286
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010831401.1 → XP_010829703.1  pyruvate kinase PKM isoform X2

    See identical proteins and their annotated locations for XP_010829703.1

    UniProtKB/TrEMBL
    A0A6P3GDG6
    Related
    ENSBBBP00000025198.1, ENSBBBT00000031417.1
    Conserved Domains (1) summary
    cd00288
    Location:42 → 530
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  2. XM_010831400.1 → XP_010829702.1  pyruvate kinase PKM isoform X1

    See identical proteins and their annotated locations for XP_010829702.1

    UniProtKB/TrEMBL
    A0A6P3GSP4
    Conserved Domains (1) summary
    cd00288
    Location:42 → 530
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

  3. XM_010831402.1 → XP_010829704.1  pyruvate kinase PKM isoform X1

    See identical proteins and their annotated locations for XP_010829704.1

    UniProtKB/TrEMBL
    A0A6P3GSP4
    Related
    ENSBBBP00000012622.1, ENSBBBT00000031419.1
    Conserved Domains (1) summary
    cd00288
    Location:42 → 530
    Pyruvate_Kinase; Pyruvate kinase (PK): Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low ...

RNA

  1. XR_824465.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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