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PTPRO protein tyrosine phosphatase receptor type O [ Rhinopithecus roxellana (golden snub-nosed monkey) ]

Gene ID: 104666396, updated on 12-Mar-2024

Summary

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Gene symbol
PTPRO
Gene description
protein tyrosine phosphatase receptor type O
See related
Ensembl:ENSRROG00000045765
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinopithecus roxellana
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Rhinopithecus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 10
Exon count:
27
Annotation release Status Assembly Chr Location
101 current ASM756505v1 (GCF_007565055.1) 10 NC_044558.1 (16393526..16666484)
100 previous assembly Rrox_v1 (GCF_000769185.1) Unplaced Scaffold NW_010808112.1 (1320683..1594382)

Chromosome 10 - NC_044558.1Genomic Context describing neighboring genes Neighboring gene RAS like estrogen regulated growth inhibitor Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene EGFR pathway substrate 8, signaling adaptor Neighboring gene 28S ribosomal protein S7, mitochondrial pseudogene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Wnt-protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cadherin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-tyrosine dephosphorylation involved in inactivation of protein kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in podocyte differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of glomerular filtration IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in GABA-ergic synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in glutamatergic synapse IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
receptor-type tyrosine-protein phosphatase O

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rhinopithecus roxellana Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM756505v1 Primary Assembly

Genomic

  1. NC_044558.1 Reference ASM756505v1 Primary Assembly

    Range
    16393526..16666484
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010368473.2 → XP_010366775.1  receptor-type tyrosine-protein phosphatase O isoform X1

    UniProtKB/TrEMBL
    A0A2K6RXM2, A0A2K6RXQ8
    Related
    ENSRROP00000045777.1
    Conserved Domains (3) summary
    cd00063
    Location:434 → 526
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14614
    Location:951 → 1195
    R-PTPc-O; catalytic domain of receptor-type tyrosine-protein phosphatase O
    pfam00041
    Location:725 → 804
    fn3; Fibronectin type III domain

  2. XM_010368474.2 → XP_010366776.1  receptor-type tyrosine-protein phosphatase O isoform X2

    UniProtKB/TrEMBL
    A0A2K6RXL9
    Related
    ENSRROP00000045781.1
    Conserved Domains (3) summary
    cd00063
    Location:434 → 526
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd14614
    Location:923 → 1167
    R-PTPc-O; catalytic domain of receptor-type tyrosine-protein phosphatase O
    pfam00041
    Location:725 → 804
    fn3; Fibronectin type III domain

  3. XM_030939691.1 → XP_030795551.1  receptor-type tyrosine-protein phosphatase O isoform X3

    Conserved Domains (1) summary
    cd14614
    Location:112 → 356
    R-PTPc-O; catalytic domain of receptor-type tyrosine-protein phosphatase O
Nucleotide Protein
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