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MTA1 metastasis associated 1 [ Struthio camelus (African ostrich) ]

Gene ID: 104142752, updated on 23-Aug-2024

Summary

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Gene symbol
MTA1
Gene description
metastasis associated 1
Locus tag
N308_02259
See related
Ensembl:ENSSCUG00000005681
Gene type
protein coding
RefSeq status
MODEL
Organism
Struthio camelus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae; Struthio
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
100 current ASM69896v1 (GCF_000698965.1) Unplaced Scaffold NW_009271010.1 (7042208..7122134)

NW_009271010.1Genomic Context describing neighboring genes Neighboring gene SEC22 homolog B, vesicle trafficking protein Neighboring gene phosphofurin acidic cluster sorting protein 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_009271010.1 Unplaced Scaffold Reference ASM69896v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone deacetylase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to ionizing radiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NuRD complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
metastasis-associated protein MTA1
Names
Metastasis-associated protein MTA1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Struthio camelus australis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69896v1 Primary Assembly

Genomic

  1. NW_009271010.1 Reference ASM69896v1 Primary Assembly

    Range
    7042208..7122134
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009672881.1 → XP_009671176.1  metastasis-associated protein MTA1

    UniProtKB/TrEMBL
    A0A093HEK0
    Related
    ENSSCUP00000007764.1, ENSSCUT00000010160.1
    Conserved Domains (6) summary
    smart00717
    Location:331 → 378
    SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
    cd11661
    Location:332 → 377
    SANT_MTA3_like; Myb-Like Dna-Binding Domain of MTA3 and related proteins
    smart00401
    Location:433 → 486
    ZnF_GATA; zinc finger binding to DNA consensus sequence [AT]GATA[AG]
    cd00202
    Location:437 → 493
    ZnF_GATA; Zinc finger DNA binding domain; binds specifically to DNA consensus sequence [AT]GATA[AG] promoter elements; a subset of family members may also bind protein; zinc-finger consensus topology is C-X(2)-C-X(17)-C-X(2)-C
    cd04709
    Location:73 → 233
    BAH_MTA; BAH, or Bromo Adjacent Homology domain, as present in MTA1 and similar proteins. The Metastasis-associated protein MTA1 is part of the NURD (nucleosome remodeling and deacetylating) complex and plays a role in cellular transformation and metastasis. BAH ...
    pfam01448
    Location:212 → 264
    ELM2; ELM2 domain
Nucleotide Protein
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