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ARHGEF7 Rho guanine nucleotide exchange factor 7 [ Struthio camelus australis ]

Gene ID: 104138639, updated on 12-Mar-2024

Summary

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Gene symbol
ARHGEF7
Gene description
Rho guanine nucleotide exchange factor 7
Locus tag
N308_11641
See related
Ensembl:ENSSCUG00000000929
Gene type
protein coding
RefSeq status
MODEL
Organism
Struthio camelus australis (sub-species: australis)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Palaeognathae; Struthioniformes; Struthionidae; Struthio
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
100 current ASM69896v1 (GCF_000698965.1) Unplaced Scaffold NW_009270154.1 (642668..724449, complement)

NW_009270154.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104138635 Neighboring gene SRY-box transcription factor 1 Neighboring gene ankyrin repeat domain 10 Neighboring gene inhibitor of growth family member 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_009270154.1 Unplaced Scaffold Reference ASM69896v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Struthio camelus australis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69896v1 Primary Assembly

Genomic

  1. NW_009270154.1 Reference ASM69896v1 Primary Assembly

    Range
    642668..724449 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009666318.1 → XP_009664613.1  rho guanine nucleotide exchange factor 7 isoform X1

    UniProtKB/TrEMBL
    A0A093H057
    Related
    ENSSCUP00000001178.1, ENSSCUT00000001623.1
    Conserved Domains (7) summary
    cd12061
    Location:85 → 138
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:169 → 346
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:377 → 475
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam00169
    Location:395 → 475
    PH; PH domain
    pfam16523
    Location:691 → 777
    betaPIX_CC; betaPIX coiled coil
    pfam16614
    Location:531 → 629
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
    pfam16615
    Location:35 → 81
    RhoGEF67_u1; Unstructured region one on RhoGEF 6 and 7

  2. XM_009666326.1 → XP_009664621.1  rho guanine nucleotide exchange factor 7 isoform X2

    UniProtKB/TrEMBL
    A0A093H057
    Related
    ENSSCUP00000001168.1, ENSSCUT00000001609.1
    Conserved Domains (6) summary
    cd12061
    Location:10 → 63
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:94 → 271
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:302 → 400
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam00169
    Location:320 → 400
    PH; PH domain
    pfam16523
    Location:557 → 643
    betaPIX_CC; betaPIX coiled coil
    pfam16614
    Location:456 → 554
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7

  3. XM_009666336.1 → XP_009664631.1  rho guanine nucleotide exchange factor 7 isoform X3

    Conserved Domains (5) summary
    cd12061
    Location:10 → 63
    SH3_betaPIX; Src Homology 3 domain of beta-Pak Interactive eXchange factor
    cd00160
    Location:94 → 271
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01225
    Location:302 → 400
    PH_Cool_Pix; Cloned out of library/PAK-interactive exchange factor pleckstrin homology (PH) domain
    pfam00169
    Location:320 → 400
    PH; PH domain
    pfam16614
    Location:456 → 554
    RhoGEF67_u2; Unstructured region two on RhoGEF 6 and 7
Nucleotide Protein
Heading Accession and Version

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