U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

SOS1 SOS Ras/Rac guanine nucleotide exchange factor 1 [ Pygoscelis adeliae (Adelie penguin) ]

Gene ID: 103925086, updated on 3-Aug-2024

Summary

Go to the top of the page Help
Gene symbol
SOS1
Gene description
SOS Ras/Rac guanine nucleotide exchange factor 1
Locus tag
AS28_12812
Gene type
protein coding
RefSeq status
MODEL
Organism
Pygoscelis adeliae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Aequornithes; Sphenisciformes; Spheniscidae; Pygoscelis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
100 current ASM69910v1 (GCF_000699105.1) Unplaced Scaffold NW_008824052.1 (700028..753695, complement)

NW_008824052.1Genomic Context describing neighboring genes Neighboring gene DExH-box helicase 57 Neighboring gene MORN repeat containing 2 Neighboring gene Rho guanine nucleotide exchange factor 33 Neighboring gene mitogen-activated protein kinase kinase kinase kinase 3

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_008824052.1 Unplaced Scaffold Reference ASM69910v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
son of sevenless homolog 1
Names
Son of sevenless 1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Pygoscelis adeliae Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69910v1 Primary Assembly

Genomic

  1. NW_008824052.1 Reference ASM69910v1 Primary Assembly

    Range
    700028..753695 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009333731.1 → XP_009332006.1  son of sevenless homolog 1

    UniProtKB/TrEMBL
    A0A093QTU9
    Conserved Domains (6) summary
    smart00229
    Location:647 → 791
    RasGEFN; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal motif
    cd00155
    Location:826 → 1065
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases. Small GTP-binding proteins of the Ras superfamily function as molecular switches in fundamental events such as signal transduction, cytoskeleton dynamics and intracellular trafficking. ...
    cd00160
    Location:251 → 438
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01261
    Location:489 → 595
    PH_SOS; Son of Sevenless (SOS) Pleckstrin homology (PH) domain
    pfam00169
    Location:495 → 596
    PH; PH domain
    cl23907
    Location:147 → 227
    H2A; Histone 2A; H2A is a subunit of the nucleosome. The nucleosome is an octamer containing two H2A, H2B, H3, and H4 subunits. The H2A subunit performs essential roles in maintaining structural integrity of the nucleosome, chromatin condensation, and binding ...
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.