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PAK6 p21 (RAC1) activated kinase 6 [ Ursus maritimus (polar bear) ]

Gene ID: 103673553, updated on 11-Mar-2024

Summary

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Gene symbol
PAK6
Gene description
p21 (RAC1) activated kinase 6
See related
Ensembl:ENSUMAG00000012924
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus maritimus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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See PAK6 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
101 current ASM1731132v1 (GCF_017311325.1) Unplaced Scaffold NW_024426119.1 (6843555..6883273)
100 previous assembly UrsMar_1.0 (GCF_000687225.1) Unplaced Scaffold NW_007907204.1 (3748874..3784698, complement)

NW_024426119.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121100196 Neighboring gene BUB1 mitotic checkpoint serine/threonine kinase B Neighboring gene uncharacterized LOC103673466 Neighboring gene uncharacterized LOC103673465 Neighboring gene ankyrin repeat domain 63

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of MAPK cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase PAK 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ursus maritimus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1731132v1 Primary Assembly

Genomic

  1. NW_024426119.1 Reference ASM1731132v1 Primary Assembly

    Range
    6843555..6883273
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040620454.1 → XP_040476388.1  serine/threonine-protein kinase PAK 6

    UniProtKB/TrEMBL
    A0A452U9W6, A0A8M1F699
    Conserved Domains (2) summary
    cd01093
    Location:10 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:385 → 681
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  2. XM_040620455.1 → XP_040476389.1  serine/threonine-protein kinase PAK 6

    UniProtKB/TrEMBL
    A0A452U9W6, A0A8M1F699
    Conserved Domains (2) summary
    cd01093
    Location:10 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:385 → 681
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6

  3. XM_040620456.1 → XP_040476390.1  serine/threonine-protein kinase PAK 6

    UniProtKB/TrEMBL
    A0A452U9W6, A0A8M1F699
    Conserved Domains (2) summary
    cd01093
    Location:10 → 55
    CRIB_PAK_like; PAK (p21 activated kinase) Binding Domain (PBD), binds Cdc42p- and/or Rho-like small GTPases; also known as the Cdc42/Rac interactive binding (CRIB) motif; has been shown to inhibit transcriptional activation and cell transformation mediated by the ...
    cd06659
    Location:385 → 681
    STKc_PAK6; Catalytic domain of the Serine/Threonine Kinase, p21-activated kinase 6
Nucleotide Protein
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