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ERN2 endoplasmic reticulum to nucleus signaling 2 [ Equus przewalskii (Przewalski's horse) ]

Gene ID: 103562658, updated on 11-Mar-2024

Summary

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Gene symbol
ERN2
Gene description
endoplasmic reticulum to nucleus signaling 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus przewalskii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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See ERN2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
100 current Burgud (GCF_000696695.1) Unplaced Scaffold NW_007675618.1 (46776..65855)

NW_007675618.1Genomic Context describing neighboring genes Neighboring gene calcineurin like EF-hand protein 2 Neighboring gene polo like kinase 1 Neighboring gene dynactin subunit 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_007675618 unplaced scaffold reference Burgud Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables unfolded protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in IRE1-mediated unfolded protein response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mRNA processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of IRE1-TRAF2-ASK1 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase/endoribonuclease IRE2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus przewalskii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Burgud Primary Assembly

Genomic

  1. NW_007675618.1 Reference Burgud Primary Assembly

    Range
    46776..65855
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008537778.1 → XP_008536000.1  serine/threonine-protein kinase/endoribonuclease IRE2

    Conserved Domains (5) summary
    cd09769
    Location:39 → 367
    Luminal_IRE1; The Luminal domain, a dimerization domain, of the Serine/Threonine protein kinase, Inositol-requiring protein 1
    cd10422
    Location:785 → 910
    RNase_Ire1; RNase domain (also known as the kinase extension nuclease domain) of Ire1
    smart00220
    Location:520 → 781
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    COG1520
    Location:42 → 238
    PQQ; Outer membrane protein assembly factor BamB, contains PQQ-like beta-propeller repeat [Cell wall/membrane/envelope biogenesis]
    cd13982
    Location:517 → 782
    STKc_IRE1; Catalytic domain of the Serine/Threonine kinase, Inositol-requiring protein 1
Nucleotide Protein
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