U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

NEDD4L NEDD4 like E3 ubiquitin protein ligase [ Chlorocebus sabaeus (green monkey) ]

Gene ID: 103244214, updated on 11-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
NEDD4L
Gene description
NEDD4 like E3 ubiquitin protein ligase
See related
Ensembl:ENSCSAG00000018158
Gene type
protein coding
RefSeq status
MODEL
Organism
Chlorocebus sabaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: Un
Exon count:
36
Annotation release Status Assembly Chr Location
102 current Vero_WHO_p1.0 (GCF_015252025.1) Unplaced Scaffold NW_023666060.1 (3882156..4244040)
100 previous assembly Chlorocebus_sabeus 1.1 (GCF_000409795.2) 18 NC_023659.1 (21326276..21683817, complement)

NW_023666060.1Genomic Context describing neighboring genes Neighboring gene ATPase phospholipid transporting 8B1 Neighboring gene 28S ribosomal protein S17, mitochondrial-like Neighboring gene probable ribosome biogenesis protein RLP24 Neighboring gene uncharacterized LOC119620482 Neighboring gene uncharacterized LOC119620524 Neighboring gene uncharacterized LOC119620483 Neighboring gene uncharacterized LOC119620484

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables sodium channel inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of sodium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dendrite morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
E3 ubiquitin-protein ligase NEDD4-like
Names
neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Chlorocebus sabaeus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Vero_WHO_p1.0

Genomic

  1. NW_023666060.1 Reference Vero_WHO_p1.0

    Range
    3882156..4244040
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008013960.2 → XP_008012151.1  E3 ubiquitin-protein ligase NEDD4-like isoform X2

    See identical proteins and their annotated locations for XP_008012151.1

    Conserved Domains (5) summary
    cd04033
    Location:21 → 153
    C2_NEDD4_NEDD4L; C2 domain present in the Human neural precursor cell-expressed, developmentally down-regulated 4 (NEDD4) and NEDD4-like (NEDD4L/NEDD42)
    smart00456
    Location:549 → 581
    WW; Domain with 2 conserved Trp (W) residues
    smart00119
    Location:642 → 971
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    PHA03247
    Location:319 → 502
    PHA03247; large tegument protein UL36; Provisional
    pfam00397
    Location:387 → 416
    WW; WW domain

  2. XM_008013968.2 → XP_008012159.1  E3 ubiquitin-protein ligase NEDD4-like isoform X4

    See identical proteins and their annotated locations for XP_008012159.1

    Conserved Domains (5) summary
    smart00456
    Location:428 → 460
    WW; Domain with 2 conserved Trp (W) residues
    smart00119
    Location:521 → 850
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    PHA03247
    Location:198 → 381
    PHA03247; large tegument protein UL36; Provisional
    pfam00397
    Location:266 → 295
    WW; WW domain
    cl14603
    Location:1 → 32
    C2; C2 domain

  3. XM_008013958.2 → XP_008012149.1  E3 ubiquitin-protein ligase NEDD4-like isoform X1

    Conserved Domains (6) summary
    cd04033
    Location:25 → 157
    C2_NEDD4_NEDD4L; C2 domain present in the Human neural precursor cell-expressed, developmentally down-regulated 4 (NEDD4) and NEDD4-like (NEDD4L/NEDD42)
    smart00456
    Location:553 → 585
    WW; Domain with 2 conserved Trp (W) residues
    smart00119
    Location:646 → 975
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd00078
    Location:622 → 976
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    cd00201
    Location:504 → 534
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    pfam00397
    Location:391 → 420
    WW; WW domain

  4. XM_008013964.2 → XP_008012155.1  E3 ubiquitin-protein ligase NEDD4-like isoform X3

    Conserved Domains (6) summary
    cd04033
    Location:25 → 157
    C2_NEDD4_NEDD4L; C2 domain present in the Human neural precursor cell-expressed, developmentally down-regulated 4 (NEDD4) and NEDD4-like (NEDD4L/NEDD42)
    smart00456
    Location:533 → 565
    WW; Domain with 2 conserved Trp (W) residues
    smart00119
    Location:626 → 955
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    cd00078
    Location:602 → 956
    HECTc; HECT domain; C-terminal catalytic domain of a subclass of Ubiquitin-protein ligase (E3). It binds specific ubiquitin-conjugating enzymes (E2), accepts ubiquitin from E2, transfers ubiquitin to substrate lysine side chains, and transfers additional ...
    cd00201
    Location:484 → 514
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    pfam00397
    Location:371 → 400
    WW; WW domain

  5. XM_037987932.1 → XP_037843860.1  E3 ubiquitin-protein ligase NEDD4-like isoform X4

    Conserved Domains (5) summary
    smart00456
    Location:428 → 460
    WW; Domain with 2 conserved Trp (W) residues
    smart00119
    Location:521 → 850
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    PHA03247
    Location:198 → 381
    PHA03247; large tegument protein UL36; Provisional
    pfam00397
    Location:266 → 295
    WW; WW domain
    cl14603
    Location:1 → 32
    C2; C2 domain

  6. XM_037987934.1 → XP_037843862.1  E3 ubiquitin-protein ligase NEDD4-like isoform X5

    Conserved Domains (4) summary
    smart00456
    Location:408 → 440
    WW; Domain with 2 conserved Trp (W) residues
    smart00119
    Location:501 → 830
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    pfam00397
    Location:246 → 275
    WW; WW domain
    cl14603
    Location:1 → 32
    C2; C2 domain

  7. XM_008013967.2 → XP_008012158.1  E3 ubiquitin-protein ligase NEDD4-like isoform X4

    See identical proteins and their annotated locations for XP_008012158.1

    Conserved Domains (5) summary
    smart00456
    Location:428 → 460
    WW; Domain with 2 conserved Trp (W) residues
    smart00119
    Location:521 → 850
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    PHA03247
    Location:198 → 381
    PHA03247; large tegument protein UL36; Provisional
    pfam00397
    Location:266 → 295
    WW; WW domain
    cl14603
    Location:1 → 32
    C2; C2 domain

  8. XM_037987933.1 → XP_037843861.1  E3 ubiquitin-protein ligase NEDD4-like isoform X4

    Conserved Domains (5) summary
    smart00456
    Location:428 → 460
    WW; Domain with 2 conserved Trp (W) residues
    smart00119
    Location:521 → 850
    HECTc; Domain Homologous to E6-AP Carboxyl Terminus with
    PHA03247
    Location:198 → 381
    PHA03247; large tegument protein UL36; Provisional
    pfam00397
    Location:266 → 295
    WW; WW domain
    cl14603
    Location:1 → 32
    C2; C2 domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.