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EPHA6 EPH receptor A6 [ Chlorocebus sabaeus (green monkey) ]

Gene ID: 103228500, updated on 11-Apr-2024

Summary

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Gene symbol
EPHA6
Gene description
EPH receptor A6
Gene type
protein coding
RefSeq status
MODEL
Organism
Chlorocebus sabaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
21
Annotation release Status Assembly Chr Location
102 current Vero_WHO_p1.0 (GCF_015252025.1) Unplaced Scaffold NW_023666041.1 (82679583..83623162)
100 previous assembly Chlorocebus_sabeus 1.1 (GCF_000409795.2) 22 NC_023663.1 (82960714..83914993, complement)

NW_023666041.1Genomic Context describing neighboring genes Neighboring gene protein RCC2-like Neighboring gene protein CDV3 homolog Neighboring gene ARL6 interacting reticulophagy regulator 1 Neighboring gene crystallin beta-gamma domain containing 3 Neighboring gene ribosomal oxygenase 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane-ephrin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ephrin type-A receptor 6

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chlorocebus sabaeus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Vero_WHO_p1.0

Genomic

  1. NW_023666041.1 Reference Vero_WHO_p1.0

    Range
    82679583..83623162
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007986132.2 → XP_007984323.1  ephrin type-A receptor 6 isoform X4

    Conserved Domains (8) summary
    cd09547
    Location:959 → 1022
    SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
    smart00454
    Location:956 → 1023
    SAM; Sterile alpha motif
    cd10484
    Location:128 → 300
    EphR_LBD_A6; Ligand Binding Domain of Ephrin type-A Receptor 6
    cd00063
    Location:425 → 532
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:624 → 932
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07699
    Location:370 → 406
    GCC2_GCC3; GCC2 and GCC3
    pfam07714
    Location:629 → 928
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:552 → 624
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  2. XM_007986128.2 → XP_007984319.1  ephrin type-A receptor 6 isoform X1

    Conserved Domains (9) summary
    cd09547
    Location:1071 → 1134
    SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
    smart00454
    Location:1068 → 1135
    SAM; Sterile alpha motif
    cd10484
    Location:128 → 300
    EphR_LBD_A6; Ligand Binding Domain of Ephrin type-A Receptor 6
    cd00063
    Location:537 → 644
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:736 → 1044
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam00041
    Location:427 → 521
    fn3; Fibronectin type III domain
    pfam07699
    Location:370 → 406
    GCC2_GCC3; GCC2 and GCC3
    pfam07714
    Location:741 → 1040
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:664 → 736
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  3. XM_007986131.2 → XP_007984322.1  ephrin type-A receptor 6 isoform X3

    Conserved Domains (8) summary
    cd09547
    Location:1029 → 1092
    SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
    smart00454
    Location:1026 → 1093
    SAM; Sterile alpha motif
    cd10484
    Location:128 → 300
    EphR_LBD_A6; Ligand Binding Domain of Ephrin type-A Receptor 6
    cd00063
    Location:537 → 644
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:736 → 1002
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam00041
    Location:427 → 521
    fn3; Fibronectin type III domain
    pfam07714
    Location:741 → 998
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:664 → 736
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  4. XM_007986130.2 → XP_007984321.1  ephrin type-A receptor 6 isoform X2

    Conserved Domains (8) summary
    cd09547
    Location:1055 → 1118
    SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
    smart00454
    Location:1052 → 1119
    SAM; Sterile alpha motif
    cd10484
    Location:128 → 300
    EphR_LBD_A6; Ligand Binding Domain of Ephrin type-A Receptor 6
    cd00063
    Location:537 → 628
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:720 → 1028
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam00041
    Location:427 → 521
    fn3; Fibronectin type III domain
    pfam07714
    Location:725 → 1024
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:648 → 720
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  5. XM_007986133.2 → XP_007984324.1  ephrin type-A receptor 6 isoform X5

    Conserved Domains (9) summary
    cd09547
    Location:955 → 1018
    SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
    smart00454
    Location:952 → 1019
    SAM; Sterile alpha motif
    cd00063
    Location:421 → 528
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:620 → 928
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam00041
    Location:311 → 405
    fn3; Fibronectin type III domain
    pfam07699
    Location:254 → 290
    GCC2_GCC3; GCC2 and GCC3
    pfam07714
    Location:625 → 924
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:548 → 620
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl02704
    Location:24 → 184
    EphR_LBD; Ligand Binding Domain of Ephrin Receptors

  6. XM_007986136.2 → XP_007984327.1  ephrin type-A receptor 6 isoform X7

    See identical proteins and their annotated locations for XP_007984327.1

    Conserved Domains (7) summary
    cd09547
    Location:915 → 978
    SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
    cd00063
    Location:381 → 488
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:580 → 888
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam00041
    Location:271 → 365
    fn3; Fibronectin type III domain
    pfam07699
    Location:212 → 250
    Ephrin_rec_like; Putative ephrin-receptor like
    pfam14575
    Location:504 → 582
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl02704
    Location:1 → 144
    EphR_LBD; Ligand Binding Domain of Ephrin Receptors

  7. XM_007986134.2 → XP_007984325.1  ephrin type-A receptor 6 isoform X6

    See identical proteins and their annotated locations for XP_007984325.1

    Conserved Domains (9) summary
    cd09547
    Location:937 → 1000
    SAM_EPH-A6; SAM domain of EPH-A6 subfamily of tyrosine kinase receptors
    smart00454
    Location:934 → 1001
    SAM; Sterile alpha motif
    cd00063
    Location:403 → 510
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:602 → 910
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam00041
    Location:293 → 387
    fn3; Fibronectin type III domain
    pfam07699
    Location:236 → 272
    GCC2_GCC3; GCC2 and GCC3
    pfam07714
    Location:607 → 906
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:530 → 602
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl02704
    Location:15 → 166
    EphR_LBD; Ligand Binding Domain of Ephrin Receptors
Nucleotide Protein
Heading Accession and Version

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