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RASA3 RAS p21 protein activator 3 [ Chlorocebus sabaeus (green monkey) ]

Gene ID: 103214860, updated on 11-Mar-2024

Summary

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Gene symbol
RASA3
Gene description
RAS p21 protein activator 3
See related
Ensembl:ENSCSAG00000017394
Gene type
protein coding
RefSeq status
MODEL
Organism
Chlorocebus sabaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
102 current Vero_WHO_p1.0 (GCF_015252025.1) Unplaced Scaffold NW_023666046.1 (49138040..49271270, complement)
100 previous assembly Chlorocebus_sabeus 1.1 (GCF_000409795.2) 3 NC_023644.1 (91848158..91974675, complement)

NW_023666046.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103214887 Neighboring gene chromosome unknown C13orf46 homolog Neighboring gene cell division cycle 16 Neighboring gene uncharacterized LOC103214864 Neighboring gene UPF3A regulator of nonsense mediated mRNA decay

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras GTPase-activating protein 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chlorocebus sabaeus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Vero_WHO_p1.0

Genomic

  1. NW_023666046.1 Reference Vero_WHO_p1.0

    Range
    49138040..49271270 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007961021.2 → XP_007959212.1  ras GTPase-activating protein 3 isoform X2

    UniProtKB/TrEMBL
    A0A0D9RXT8
    Related
    ENSCSAP00000013427.1
    Conserved Domains (7) summary
    smart00107
    Location:679 → 714
    BTK; Bruton's tyrosine kinase Cys-rich motif
    cd04010
    Location:146 → 288
    C2B_RasA3; C2 domain second repeat present in RAS p21 protein activator 3 (RasA3)
    cd08401
    Location:13 → 133
    C2A_RasA2_RasA3; C2 domain first repeat present in RasA2 and RasA3
    cd05134
    Location:297 → 565
    RasGAP_RASA3; Ras-GTPase Activating Domain of RASA3
    smart00323
    Location:275 → 614
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd13371
    Location:562 → 686
    PH_GAP1_mammal-like; GAP1(IP4BP) pleckstrin homology (PH) domain
    pfam00169
    Location:577 → 676
    PH; PH domain

  2. XM_038007934.1 → XP_037863862.1  ras GTPase-activating protein 3 isoform X3

    Conserved Domains (3) summary
    smart00107
    Location:296 → 331
    BTK; Bruton's tyrosine kinase Cys-rich motif
    cd13371
    Location:179 → 303
    PH_GAP1_mammal-like; GAP1(IP4BP) pleckstrin homology (PH) domain
    cl02569
    Location:1 → 182
    RasGAP; Ras GTPase Activating Domain

  3. XM_007961024.2 → XP_007959215.1  ras GTPase-activating protein 3 isoform X1

    See identical proteins and their annotated locations for XP_007959215.1

    Conserved Domains (7) summary
    smart00107
    Location:647 → 682
    BTK; Bruton's tyrosine kinase Cys-rich motif
    cd04010
    Location:114 → 256
    C2B_RasA3; C2 domain second repeat present in RAS p21 protein activator 3 (RasA3)
    cd08401
    Location:1 → 101
    C2A_RasA2_RasA3; C2 domain first repeat present in RasA2 and RasA3
    cd05134
    Location:265 → 533
    RasGAP_RASA3; Ras-GTPase Activating Domain of RASA3
    smart00323
    Location:243 → 582
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd13371
    Location:530 → 654
    PH_GAP1_mammal-like; GAP1(IP4BP) pleckstrin homology (PH) domain
    pfam00169
    Location:545 → 644
    PH; PH domain
Nucleotide Protein
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