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RASGRF2 Ras protein specific guanine nucleotide releasing factor 2 [ Python bivittatus (Burmese python) ]

Gene ID: 103062438, updated on 11-Mar-2024

Summary

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Gene symbol
RASGRF2
Gene description
Ras protein specific guanine nucleotide releasing factor 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Python bivittatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Henophidia; Pythonidae; Python
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
102 current Python_molurus_bivittatus-5.0.2 (GCF_000186305.1) Unplaced Scaffold NW_006532233.1 (474850..555145, complement)

NW_006532233.1Genomic Context describing neighboring genes Neighboring gene acyl-CoA thioesterase 12 Neighboring gene zinc finger CCHC-type containing 9 Neighboring gene creatine kinase, mitochondrial 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006532233 Unplaced Scaffold Reference Python_molurus_bivittatus-5.0.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras-specific guanine nucleotide-releasing factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Python bivittatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Python_molurus_bivittatus-5.0.2 Primary Assembly

Genomic

  1. NW_006532233.1 Reference Python_molurus_bivittatus-5.0.2 Primary Assembly

    Range
    474850..555145 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007422665.3 → XP_007422727.1  ras-specific guanine nucleotide-releasing factor 2

    UniProtKB/TrEMBL
    A0A9F2N6I1
    Conserved Domains (7) summary
    smart00147
    Location:904 → 1140
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
    pfam00169
    Location:384 → 491
    PH; PH domain
    pfam00618
    Location:542 → 591
    RasGEF_N; RasGEF N-terminal motif
    pfam00621
    Location:151 → 332
    RhoGEF; RhoGEF domain
    pfam09786
    Location:617 → 755
    CytochromB561_N; Cytochrome B561, N terminal
    cl02520
    Location:806 → 878
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    cl17171
    Location:1 → 62
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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