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LRP2 LDL receptor related protein 2 [ Balaenoptera acutorostrata (minke whale) ]

Gene ID: 103004235, updated on 11-Mar-2024

Summary

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Gene symbol
LRP2
Gene description
LDL receptor related protein 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Balaenoptera acutorostrata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti; Balaenopteridae; Balaenoptera
Orthologs
human mouse all
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Genomic context

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See LRP2 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
79
Annotation release Status Assembly Chr Location
RS_2023_06 current mBalAcu1.1 (GCF_949987535.1) 8 NC_080071.1 (30533472..30732866, complement)
101 previous assembly BalAcu1.0 (GCF_000493695.1) Unplaced Scaffold NW_006727463.1 (30942311..31141336, complement)

Chromosome 8 - NC_080071.1Genomic Context describing neighboring genes Neighboring gene ATP synthase subunit g, mitochondrial-like Neighboring gene dehydrogenase/reductase 9 Neighboring gene transfer RNA serine (anticodon ACU) Neighboring gene phosphatidylinositol N-acetylglucosaminyltransferase subunit C-like Neighboring gene Bardet-Biedl syndrome 5 Neighboring gene kelch like family member 41 Neighboring gene FAST kinase domains 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
low-density lipoprotein receptor-related protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_949987535.1-RS_2023_06

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mBalAcu1.1

Genomic

  1. NC_080071.1 Reference mBalAcu1.1

    Range
    30533472..30732866 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007183233.2 → XP_007183295.1  low-density lipoprotein receptor-related protein 2

    UniProtKB/TrEMBL
    A0A384A7G8
    Conserved Domains (11) summary
    smart00192
    Location:3631 → 3663
    LDLa; Low-density lipoprotein receptor domain class A
    smart00135
    Location:503 → 548
    LY; Low-density lipoprotein-receptor YWTD domain
    smart00179
    Location:4004 → 4035
    EGF_CA; Calcium-binding EGF-like domain
    cd00112
    Location:3718 → 3751
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd05819
    Location:2465 → 2502
    NHL; NHL repeat [structural motif]
    pfam00058
    Location:4194 → 4234
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    pfam12662
    Location:3128 → 3151
    cEGF; Complement Clr-like EGF-like
    pfam14670
    Location:1354 → 1389
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00057
    Location:3143 → 3186
    vWFA; Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of ...
    cl00104
    Location:65 → 100
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cl18310
    Location:2416 → 2614
    NHL; NHL repeat unit of beta-propeller proteins
Nucleotide Protein
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